Trial reportBMC geriatrics2022
Sex differences in the association of physical activity levels and vitamin D with obesity, sarcopenia, and sarcopenic obesity: a cross-sectional study.
Trial report in BMC geriatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Pooled it
- The Implication of Nutrition on the Prevention and Improvement of Age-Related Sarcopenic Obesity: A Systematic Review.The journal of nutrition, health & aging · 2023Pooled it
- Article
- Vitamin D as a Modulator of Sarcopenia in Women: Interactions with Dietary Patterns and Physical Exercise.Nutrients · 2026Review
- Dietary patterns and the progression from obesity to sarcopenic obesity in older adults: a prospective cohort study.BMC geriatrics · 2026Article
- The feasibility of using deep learning technologies to preliminarily identify patients with advanced knee osteoarthritis via smartphone videos.Journal of neuroengineering and rehabilitation · 2026Article
- Article
- Associations of high protein supplements with gut microbiota and skeletal muscle mass in hospitalized older people.BMC geriatrics · 2025Article
- Oral-Sarcopenia nexus in health disparities: chewing and blood mediated pathways in a Chinese aging cohort.BMC oral health · 2025Observational
- Study on body composition characteristics and influencing factors of sarcopenia status among older adults in Shanghai: a cross-sectional study.Journal of health, population, and nutrition · 2025Article
- Vitamin D and Sarcopenia: Implications for Muscle Health.Biomedicines · 2025Review
- Comparative efficacy of exercise, nutrition, and combined exercise and nutritional interventions in older adults with sarcopenic obesity: a protocol for systematic review and network meta-analysis.Systematic reviews · 2025Article
- Associations between hypovitaminosis D, adiposity indices and insulin resistance in adolescents: mediation analyses from NHANES 2011-2018.Nutrition & diabetes · 2025Article
- The Effects of Vitamin D on Muscle Strength Are Influenced by Testosterone Levels.Journal of cachexia, sarcopenia and muscle · 2025Article
- Age but not vitamin D is related to sarcopenia in vitamin D sufficient male elderly in rural China.Scientific reports · 2025Article
- Evaluating the weight-adjusted waist index as a predictive tool for sarcopenia and mortality risk.Eating and weight disorders : EWD · 2025Article
- Sex-specific prognostic utility of the sarcopenia index in all-cause mortality risk for patients with heart failure.Frontiers in nutrition · 2025Article
- Association between human herpesvirus 6 status and sarcopenia risk: a UK biobank cohort study with sex-specific patterns and telomere length modification.Frontiers in immunology · 2025Article
- Risk Factors for Sarcopenia in Women with Type 2 Diabetes and the Effects of Metformin: A Cross-Sectional Study of 7,731 Patients from the UK Biobank.International journal of women's health · 2025Article
- Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe relationship between vitamin D and sarcopenia was inconsistent between men and women. Physical activity (PA) may interact with vitamin D on sarcopenia. However, the sex-specific relationships of vitamin D, PA and sarcopenia have yet elucidated. We aimed to examine the sex differences in the relation between vitamin D status, PA levels, obesity and sarcopenia in community-dwelling middle-aged and older adults, as well as whether vitamin D status is a modifier in the relationship between PA and sarcopenia.
methodsThe current study was a cross-sectional study based on the baseline survey of the West China Health and Aging Trend (WCHAT) study. A total of 3713 participants aged ≥ 50y were included in our study. Sarcopenia was defined according to the Asian Working Group for Sarcopenia (AWGS) 2019 consensus. Obesity was defined by body mass index (BMI) (≥ 28 kg/m2) and body fat mass percentage (≥ 60th percentile in each sex group). 25-hydroxyvitamin D was measured by chemiluminescent microparticle immunoassay and PA was evaluated by a validated China Leisure Time Physical Activity Questionnaire (CLTPAQ). Multinomial logistic regression was performed to examine the relationship between PA, vitamin D and sarcopenia and obesity.
resultsLow PA was significantly associated with higher odds of sarcopenia in women only (OR = 1.70,95%CI:1.18,2.46, p < 0.01). Vitamin D deficiency was only associated with sarcopenia in men (OR = 1.85,95%CI: 1.27,2.69, p < 0.01). Low PA was significantly associated with obesity, sarcopenia, and sarcopenic obesity only in participants with serum 25(OH)D < 20 ng/ml.
conclusionsThe role of vitamin D and PA in obesity and sarcopenia was different between men and women, and the relationship between PA and sarcopenia was modified by serum vitamin D status. These findings highlighted the need to supplement vitamin D in individuals with physical inactivity and provide different interventions strategies to sarcopenia in men and women.
trial registrationClinical trial number: ChiCTR1800018895.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.