Evidence map›Paper›PMID 36434312›Full record

ArticleNeuroradiology2023

Evaluation of the cerebrovascular reactivity in patients with Moyamoya Angiopathy by use of breath-hold fMRI: investigation of voxel-wise hemodynamic delay correction in comparison to [

Leonie Zerweck, Till-Karsten Hauser, Constantin Roder, Ganna Blazhenets, Nadia Khan, Ulrike Ernemann, Philipp T Meyer, Uwe Klose

Open access · hybridAbstract read
In one paragraph

Article in Neuroradiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Leonie ZerweckDepartment of Diagnostic and Interventional Neuroradiology, University Hospital Tuebingen, Hoppe-Seyler-Straße 3, 72076, Tuebingen, Germany. Leonie.Zerweck@med.uni-tuebingen.de.ORCID http://orcid.org/0000-0003-4105-5131
Till-Karsten HauserDepartment of Diagnostic and Interventional Neuroradiology, University Hospital Tuebingen, Hoppe-Seyler-Straße 3, 72076, Tuebingen, Germany.ORCID http://orcid.org/0000-0001-7604-3419
Constantin RoderDepartment of Neurosurgery, University Hospital Tuebingen, Tuebingen, Germany.ORCID http://orcid.org/0000-0003-4487-2807
Ganna BlazhenetsDepartment of Nuclear Medicine, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.ORCID http://orcid.org/0000-0003-2419-7373
Nadia KhanDepartment of Neurosurgery, University Hospital Tuebingen, Tuebingen, Germany.ORCID http://orcid.org/0000-0001-5179-5243
Ulrike ErnemannDepartment of Diagnostic and Interventional Neuroradiology, University Hospital Tuebingen, Hoppe-Seyler-Straße 3, 72076, Tuebingen, Germany.ORCID http://orcid.org/0000-0003-1330-1235
Philipp T MeyerDepartment of Nuclear Medicine, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.ORCID http://orcid.org/0000-0001-8336-750X
Uwe KloseDepartment of Diagnostic and Interventional Neuroradiology, University Hospital Tuebingen, Hoppe-Seyler-Straße 3, 72076, Tuebingen, Germany.ORCID http://orcid.org/0000-0001-5236-3450
University of Freiburg · DEUniversity Children's Hospital Zurich · CHUniversity of Tübingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePatients with Moyamoya Angiopathy (MMA) require hemodynamic assessment to evaluate the risk of stroke. Hemodynamic evaluation by use of breath-hold-triggered fMRI (bh-fMRI) was proposed as a readily available alternative to the diagnostic standard [

methodsbh-fMRI data sets of 22 patients with MMA were evaluated without and with voxel-wise delay correction within different shift ranges and compared to the corresponding [

resultsThe study revealed a high mean cross-correlation (r = 0.79, p < 0.001) between bh-fMRI and [

conclusionVoxel-wise delay correction, in particular with shift ranges with high cutoff, should be used critically as it can lead to false-negative results in regions with impaired CVR and a lower correlation to the diagnostic standard [

Indexed as

Magnetic Resonance ImagingMoyamoya DiseaseBrainCerebrovascular CirculationHemodynamicsHumansWaterWater[15O]water PETBreath-hold fMRICerebral perfusion reserve capacityCerebrovascular reactivityMoyamoya Angiopathy

Identifiers

PMID36434312
PMCPMC9905170
OpenAlexW4310077699

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.