Evidence map›Paper›PMID 36434134›Full record

ArticleArchives of microbiology2022

Anti-Aspergillus fumigatus IgG in patients with bronchiectasis and its relationship with clinical outcome.

Mariana Rodrigues Trápaga, Vanice Rodrigues Poester, Karine Ortiz Sanchotene, Aryse Martins Melo, Jéssica Louise Benelli, Rossana Patricia Basso, Gabriel Baracy Klafke, Daniela Fernandes Ramos, Cristina Veríssimo, Raquel Sabino and 2 more

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Archives of microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Mariana Rodrigues TrápagaLaboratory of Mycology, Faculty of Medicine, Federal University of Rio Grande, Health Campus, Visconde de Paranaguá 102, Center, Rio Grande, RS, 96200-400, Brazil.
Vanice Rodrigues PoesterLaboratory of Mycology, Faculty of Medicine, Federal University of Rio Grande, Health Campus, Visconde de Paranaguá 102, Center, Rio Grande, RS, 96200-400, Brazil.
Karine Ortiz SanchotenePost-Graduate Program in Health Sciences, Federal University of Rio Grande, Rio Grande, RS, 96200-400, Brazil.
Aryse Martins MeloNational Institute of Health, Dr. Ricardo Jorge, Av. Padre Cruz, 1649-016, Lisbon, Portugal.
Jéssica Louise BenelliLaboratory of Mycology, Faculty of Medicine, Federal University of Rio Grande, Health Campus, Visconde de Paranaguá 102, Center, Rio Grande, RS, 96200-400, Brazil.
Rossana Patricia BassoPost-Graduate Program in Health Sciences, Federal University of Rio Grande, Rio Grande, RS, 96200-400, Brazil.
Gabriel Baracy KlafkeLaboratory of Mycology, Faculty of Medicine, Federal University of Rio Grande, Health Campus, Visconde de Paranaguá 102, Center, Rio Grande, RS, 96200-400, Brazil.
Daniela Fernandes RamosPost-Graduate Program in Health Sciences, Federal University of Rio Grande, Rio Grande, RS, 96200-400, Brazil.
Cristina VeríssimoNational Institute of Health, Dr. Ricardo Jorge, Av. Padre Cruz, 1649-016, Lisbon, Portugal.
Raquel SabinoNational Institute of Health, Dr. Ricardo Jorge, Av. Padre Cruz, 1649-016, Lisbon, Portugal.
David A StevensCalifornia Institute for Medical Research, San Jose, CA, USA.
Melissa Orzechowski XavierLaboratory of Mycology, Faculty of Medicine, Federal University of Rio Grande, Health Campus, Visconde de Paranaguá 102, Center, Rio Grande, RS, 96200-400, Brazil. melissaxavierfurg@gmail.com.
Universidade Federal do Rio Grande · BRNational Institute of Health Dr. Ricardo Jorge · PTHospital Universitário Onofre Lopes · BRStanford University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aspergillosis is a mycosis, most commonly affecting the airways. This mycosis can worsen the clinical condition of patients with concurrent lung diseases. We assayed for the presence of serum anti-A. fumigatus IgG in bronchiectasis patients from a tertiary hospital in south Brazil and evaluated the relationship with clinical outcome. Thirty-one patients with bronchiectasis, without cystic fibrosis, were included. Clinical and epidemiological data were collected from all participants. Positive serological tests were detected in 13% (4/31) of the patients. The mortality rate for the year following the assay was, in the seropositive group, 75% (3/4), whereas in the seronegative group, 15% (4/27). An illustrative case is also shown and discussed. Our study highlights the diagnostic challenge and the possible impact of Aspergillus infection on these patients, indicating the necessity of more and larger investigations in the field.

Indexed as

AspergillosisBronchiectasisCystic FibrosisBrazilHumansImmunoglobulin GImmunoglobulin GAspergillosisAspergillus IgGELISAFungal diseaseImmunodiffusion

Identifiers

PMID36434134
OpenAlexW4310081638

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.