Evidence map›Paper›PMID 36434073›Full record

ArticleScientific reports2022

Tobacco use and risk of COVID-19 infection in the Finnish general population.

Sebastián Peña, Katja Ilmarinen, Laura Kestilä, Suvi Parikka, Sanna Kärkkäinen, Ida Henriette Caspersen, Ahmed Nabil Shaaban, Per Magnus, Maria Rosaria Galanti, Sakari Karvonen

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Impact of Smoking on Household SARS-CoV-2 Transmission.Healthcare (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Sebastián PeñaDepartment of Public Health and Welfare, Finnish Institute for Health and Welfare, Mannerheimintie 166, 00271, Helsinki, Finland. sebastian.penafajuri@thl.fi.
Katja IlmarinenDepartment of Public Health and Welfare, Finnish Institute for Health and Welfare, Mannerheimintie 166, 00271, Helsinki, Finland.
Laura KestiläDepartment of Public Health and Welfare, Finnish Institute for Health and Welfare, Mannerheimintie 166, 00271, Helsinki, Finland.
Suvi ParikkaDepartment of Public Health and Welfare, Finnish Institute for Health and Welfare, Mannerheimintie 166, 00271, Helsinki, Finland.
Sanna KärkkäinenDepartment of Public Health and Welfare, Finnish Institute for Health and Welfare, Mannerheimintie 166, 00271, Helsinki, Finland.
Ida Henriette CaspersenCentre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.
Ahmed Nabil ShaabanDepartment of Global Public Health, Karolinska Institutet, Solna, Sweden.
Per MagnusCentre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway.
Maria Rosaria GalantiDepartment of Global Public Health, Karolinska Institutet, Solna, Sweden.
Sakari KarvonenDepartment of Public Health and Welfare, Finnish Institute for Health and Welfare, Mannerheimintie 166, 00271, Helsinki, Finland.
Finnish Institute for Health and Welfare · FIKarolinska Institutet · SENorwegian Institute of Public Health · NOCentre for Palaeogenetics · SE

Funding

Nordforsk 105544
6 · The paper itself

Abstract

Empirical evidence, primarily based on hospital-based or voluntary samples, suggests that current smokers have a lower risk of COVID-19 infection than never smokers. In this study, we used nationally representative data to examine the association between tobacco use and the risk of having a confirmed COVID-19 case. We explored several forms of tobacco use, contributing to separate the role of nicotine from smoking. We used data from 44,199 participants from three pooled national health surveys in Finland (FinSote 2018-2020). The primary outcome was a confirmed COVID-19 case. We examined current smoking, moist smokeless tobacco (snus), e-cigarettes with and without nicotine and nicotine replacement therapy products. Current daily smokers had a relative risk of 1.12 of a confirmed COVID-19 case (95% CI 0.65; 1.94) in fully adjusted models compared with never smokers. Current snus use was associated with a 68% higher risk of a confirmed COVID-19 case (RR 1.68, 95% CI 1.02; 2.75) than never users. We did not find conclusive evidence of associations between e-cigarettes with and without nicotine and nicotine replacement therapy products and the risk of confirmed COVID-19 cases. Our findings suggest that nicotine might not have a protective role in the risk of COVID-19 as previously hypothesized.

Indexed as

COVID-19Electronic Nicotine Delivery SystemsSmoking CessationFinlandHumansNicotineTobacco UseTobacco Use Cessation DevicesNicotine

Identifiers

PMID36434073
PMCPMC9700668
OpenAlexW4310056730

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.