Evidence map›Paper›PMID 36433959›Full record

ArticleNature communications2022

mTORC1 signaling facilitates differential stem cell differentiation to shape the developing murine lung and is associated with mitochondrial capacity.

Kuan Zhang, Erica Yao, Ethan Chuang, Biao Chen, Evelyn Y Chuang, Pao-Tien Chuang

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Mesenchymal stromal/stem cells and bronchopulmonary dysplasia.Frontiers in cell and developmental biology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kuan ZhangCardiovascular Research Institute, University of California, San Francisco, CA, USA.ORCID 0000-0002-9723-1328
Erica YaoCardiovascular Research Institute, University of California, San Francisco, CA, USA.
Ethan ChuangCardiovascular Research Institute, University of California, San Francisco, CA, USA.
Biao ChenCardiovascular Research Institute, University of California, San Francisco, CA, USA.
Evelyn Y ChuangCardiovascular Research Institute, University of California, San Francisco, CA, USA.
Pao-Tien ChuangCardiovascular Research Institute, University of California, San Francisco, CA, USA. pao-tien.chuang@ucsf.edu.ORCID 0000-0002-8961-8653
University of California, San Francisco · US

Funding

Molecular mechanisms of alveolar development and regenerationR01HL142876 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHUANG, PAO-TIEN · 2018 to 2021
$2.1M
NHLBI NIH HHS R01 HL142876
6 · The paper itself

Abstract

Formation of branched organs requires sequential differentiation of stem cells. In this work, we find that the conducting airways derived from SOX2

Indexed as

CystsLungMechanistic Target of Rapamycin Complex 1AnimalsCell DifferentiationMammalsMiceMitochondriaTOR Serine-Threonine KinasesMechanistic Target of Rapamycin Complex 1mTOR protein, mouseTOR Serine-Threonine Kinases

Identifiers

PMID36433959
PMCPMC9700781
OpenAlexW4309962036

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.