Evidence map›Paper›PMID 36433946›Full record

ArticleNature communications2022

Postnatal expansion of mesenteric lymph node stromal cells towards reticular and CD34

Joern Pezoldt, Carolin Wiechers, Mangge Zou, Maria Litovchenko, Marjan Biocanin, Michael Beckstette, Katarzyna Sitnik, Martina Palatella, Guido van Mierlo, Wanze Chen and 9 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

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  10. Lymph node stromal cell responses to perinatal T cell waves, a temporal atlas.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 6 institutions in 3 countries.

Joern Pezoldt *Department Experimental Immunology, Helmholtz Centre for Infection Research, 38124, Braunschweig, Germany.ORCID 0000-0001-7143-5691
Carolin Wiechers *Department Experimental Immunology, Helmholtz Centre for Infection Research, 38124, Braunschweig, Germany.
Mangge ZouDepartment Experimental Immunology, Helmholtz Centre for Infection Research, 38124, Braunschweig, Germany.ORCID 0000-0001-6363-4260
Maria LitovchenkoLaboratory of Systems Biology and Genetics, École Polytechnique Fédérale de Lausanne, 1015, Lausanne, Switzerland.ORCID 0000-0003-1868-4933
Marjan BiocaninLaboratory of Systems Biology and Genetics, École Polytechnique Fédérale de Lausanne, 1015, Lausanne, Switzerland.
Michael BeckstetteDepartment Experimental Immunology, Helmholtz Centre for Infection Research, 38124, Braunschweig, Germany.
Katarzyna SitnikInstitute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, Vienna, Austria.ORCID 0000-0002-6965-0322
Martina PalatellaDepartment Experimental Immunology, Helmholtz Centre for Infection Research, 38124, Braunschweig, Germany.ORCID 0000-0003-1986-8590
Guido van MierloLaboratory of Systems Biology and Genetics, École Polytechnique Fédérale de Lausanne, 1015, Lausanne, Switzerland.
Wanze ChenLaboratory of Systems Biology and Genetics, École Polytechnique Fédérale de Lausanne, 1015, Lausanne, Switzerland.ORCID 0000-0002-7946-3336
Vincent GardeuxLaboratory of Systems Biology and Genetics, École Polytechnique Fédérale de Lausanne, 1015, Lausanne, Switzerland.ORCID 0000-0001-8954-2161
Stefan FloessDepartment Experimental Immunology, Helmholtz Centre for Infection Research, 38124, Braunschweig, Germany.ORCID 0000-0001-9904-4094
Maria EbelDepartment Experimental Immunology, Helmholtz Centre for Infection Research, 38124, Braunschweig, Germany.
Julie RusseilLaboratory of Systems Biology and Genetics, École Polytechnique Fédérale de Lausanne, 1015, Lausanne, Switzerland.ORCID 0000-0002-0880-9483
Panagiota ArampatziCore Unit Systems Medicine, University of Wuerzburg, 97080, Wuerzburg, Germany.ORCID 0000-0001-7925-8984
Ehsan VafardanejadHelmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz Center for Infection Research (HZI), 97080, Würzburg, Germany.
Antoine-Emmanuel SalibaHelmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz Center for Infection Research (HZI), 97080, Würzburg, Germany.ORCID 0000-0001-8539-2784
Bart Deplancke *Laboratory of Systems Biology and Genetics, École Polytechnique Fédérale de Lausanne, 1015, Lausanne, Switzerland.ORCID 0000-0001-9935-843X
Jochen Huehn *Department Experimental Immunology, Helmholtz Centre for Infection Research, 38124, Braunschweig, Germany. jochen.huehn@helmholtz-hzi.de.ORCID 0000-0001-8071-1379
École Polytechnique Fédérale de Lausanne · CHHelmholtz Centre for Infection Research · DEHelmholtz Institute for RNA-based Infection Research · DEBielefeld University · DEMedizinische Hochschule Hannover · DEUniversity of Veterinary Medicine Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gut-draining mesenteric lymph nodes (LN) provide the framework to shape intestinal adaptive immune responses. Based on the transcriptional signatures established by our previous work, the composition and immunomodulatory function of LN stromal cells (SC) vary according to location. Here, we describe the single-cell composition and development of the SC compartment within mesenteric LNs derived from postnatal to aged mice. We identify CD34

Indexed as

Lymph NodesStromal CellsAnimalsAntigens, CD34Cell Adhesion MoleculesMiceMice, Inbred C57BLAntigens, CD34Cell Adhesion Molecules

Identifiers

PMID36433946
PMCPMC9700677
OpenAlexW4310061942

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.