Evidence map›Paper›PMID 36432982›Full record

ReviewPolymers2022

Supramolecular Combination Cancer Therapy Based on Macrocyclic Supramolecular Materials.

Yilin Li, Yuteng Su, Zhaoxiang Li, Yueyue Chen

Abstract readReview
In one paragraph

Review in Polymers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yilin LiDepartment of Toxicology and Sanitary Chemistry, School of Public Health, Beijing Key Laboratory of Environment Toxicology, Capital Medical University, Beijing 100069, China.
Yuteng SuDepartment of Toxicology and Sanitary Chemistry, School of Public Health, Beijing Key Laboratory of Environment Toxicology, Capital Medical University, Beijing 100069, China.
Zhaoxiang LiDepartment of Toxicology and Sanitary Chemistry, School of Public Health, Beijing Key Laboratory of Environment Toxicology, Capital Medical University, Beijing 100069, China.
Yueyue ChenDepartment of Toxicology and Sanitary Chemistry, School of Public Health, Beijing Key Laboratory of Environment Toxicology, Capital Medical University, Beijing 100069, China.ORCID 0000-0002-3283-0039

Funding

Beijing Natural Science Foundation 2212026Beijing Natural Science Foundation L223015National Natural Science Foundation of China 21805197
6 · The paper itself

Abstract

Supramolecular combination therapy adopts supramolecular materials to design intelligent drug delivery systems with different strategies for cancer treatments. Thereinto, macrocyclic supramolecular materials play a crucial role in encapsulating anticancer drugs to improve anticancer efficiency and decrease toxicity towards normal tissue by host-guest interaction. In general, chemotherapy is still common therapy for solid tumors in clinics. However, supramolecular combination therapy can overcome the limitations of the traditional single-drug chemotherapy in the laboratory findings. In this review, we summarized the combination chemotherapy, photothermal chemotherapy, and gene chemotherapy based on macrocyclic supramolecular materials. Finally, the application prospects in supramolecular combination therapy are discussed.

Indexed as

combination therapycucurbiturilcyclodextrinmultivalent supramolecular assemblypillararene

Identifiers

PMID36432982
PMCPMC9696801

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.