Evidence map›Paper›PMID 36432616›Full record

ArticleNutrients2022

Relationship of Early Anemia with Neurodevelopment and Brain Injury in Very Low Birth Weight Preterm Infants-A Prospective Cohort Study.

Xiaotong Wang, Jiajia Jing, Saijun Huang, Xiaoying He, Pingming Gao, Hailin Li, Zongyu Lin, Per Torp Sangild, Yanna Zhu

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Xiaotong WangDepartment of Maternal and Child Health, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China.
Jiajia JingDepartment of Maternal and Child Health, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China.
Saijun HuangDepartment of Child Health Care, Foshan Woman and Children's Hospital, Foshan 528000, China.
Xiaoying HeDepartment of Child Health Care, Foshan Woman and Children's Hospital, Foshan 528000, China.
Pingming GaoDepartment of Pediatrics, Foshan Woman and Children's Hospital, Foshan 528000, China.
Hailin LiDepartment of Maternal and Child Health, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China.
Zongyu LinDepartment of Maternal and Child Health, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China.
Per Torp SangildDepartment of Pediatrics and Adolescent Medicine, Rigshospitalet, DK-1870 Copenhagen, Denmark.
Yanna ZhuDepartment of Maternal and Child Health, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China.ORCID 0000-0003-4160-3695
Sun Yat-sen University · CNFoshan Maternity and Child Health Care Hospital · CNRigshospitalet · DK

Funding

the Research fund for the Guangdong Provincial Natural Science Foundation 2021A1515010439the Sanming Project of Medicine in Shenzhen SZSM201803061
6 · The paper itself

Abstract

Anemia is associated with neurodevelopmental delays and brain injury in infants and toddlers, but whether early anemia has a similar effect in neonatal preterm infants is largely unknown. Thus, this study aimed to determine the relationship of early anemia with neurodevelopment and brain injury in very-low-birth-weight (VLBW) preterm infants within the neonatal period. A prospective cohort study including 110 VLBW preterm infants was conducted in Southern China from 2016 to 2018. All participants were followed from birth to 1 month corrected age. Early anemia is defined as hemoglobin of ≤145 g/L within the first week after birth. The non-anemic group (control group, N = 55) was 1:1 matched with the early anemia group (N = 55) according to birth weight and gestational age. Neurodevelopment at 1 month corrected age and brain injury within 1 month corrected age were measured by neonatal behavioral neurological assessments (NBNA) and cranial ultrasound, respectively. Compared to the control group, the early anemia group had a lower score in behavioral ability in the NBNA test [11 (10-12) vs. 10 (9.5-11),

Indexed as

AnemiaBrain InjuriesHumansInfantInfant, NewbornInfant, PrematureInfant, Very Low Birth WeightProspective Studiesanemianeurodevelopmentpretermvery-low-birth-weight infants

Identifiers

PMID36432616
PMCPMC9695480
OpenAlexW4309720099

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.