Evidence map›Paper›PMID 36432609›Full record

ArticleNutrients2022

Effectiveness of Acute Malnutrition Treatment at Health Center and Community Levels with a Simplified, Combined Protocol in Mali: An Observational Cohort Study.

Suvi T Kangas, Bethany Marron, Zachary Tausanovitch, Elizabeth Radin, Josiane Andrianarisoa, Salimou Dembele, Césaire T Ouédraogo, Issa Niamanto Coulibaly, Marie Biotteau, Bareye Ouologuem and 5 more

Registry-linked trialAbstract read
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In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07592260 (OptiMAx), which is not on this map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07592260 narecruitingnot on this mapstarted 2025, after this paper: background citation

OptiMAx: Incentivizing EPI Vaccination Via Distribution of SQ-LNS Nutritional Supplementation to Children From Age 6-11 Months Until 18 Months of Age in Rural Chad and Niger, With a Cost Effectiveness Analysis Protocol for a Research Study Nested in the OptiMA Research Study in Ngouri Health District, Lake Region, Chad and Mirriah Health District, Zinder Region, Niger

TypeinterventionalSponsorAlliance for International Medical ActionRan2025 to 2026Enrolled20,000ConditionsMalnutrition Severe, VaccinationArmssmall quantity lipid-based supplement (SQ-LNS)
3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Suvi T KangasInternational Rescue Committee, New York, NY, USA.ORCID 0000-0003-1477-7649
Bethany MarronInternational Rescue Committee, New York, NY, USA.
Zachary TausanovitchInternational Rescue Committee, New York, NY, USA.
Elizabeth RadinInternational Rescue Committee, New York, NY, USA.
Josiane AndrianarisoaInternational Rescue Committee, Bamako, Mali.
Salimou DembeleInternational Rescue Committee, Bamako, Mali.
Césaire T OuédraogoInternational Rescue Committee, Bamako, Mali.
Issa Niamanto CoulibalyInternational Rescue Committee, Bamako, Mali.
Marie BiotteauInternational Rescue Committee, New York, NY, USA.
Bareye OuologuemNutrition Division, Ministry of Health, Bamako, Mali.
Soumaila DaouNara District Health Unit, Nara, Mali.
Fatoumata TraoréInternational Rescue Committee, Bamako, Mali.
Issiaka TraoréInternational Rescue Committee, Bamako, Mali.
Marc NeneUnited Nations Children's Fund, Bamako, Mali.
Jeanette BaileyInternational Rescue Committee, New York, NY, USA.

Funding

Christina Kirby and Joshua Kulkin Foundation NAEuropean Commission Humanitarian Office ECHO/-WF/BUD/2018/91050, ECHO/-WF/BUD/2019/91032, ECHO/-WF/BUD/2020/91006, ECHO/MLI/EDF/2020/01003Google Camp AWF-2019-35787the Rockefeller Foundation NAthe Thompson Family Foundation NA
6 · The paper itself

Abstract

A simplified, combined protocol was created that admits children with a mid-upper-arm circumference (MUAC) of <125 mm or edema to malnutrition treatment with ready-to-use therapeutic food (RUTF) that involves prescribing two daily RUTF sachets to children with MUAC < 115 mm or edema and one daily sachet to those with 115 mm ≤ MUAC < 125 mm. This treatment was previously shown to result in non-inferior programmatic outcomes compared with standard treatment. We aimed at observing its effectiveness in a routine setting at scale, including via delivery by community health workers (CHWs). A total of 27,800 children were admitted to the simplified, combined treatment. Treatment resulted in a 92% overall recovery, with a mean length of stay of 40 days and a mean RUTF consumption of 62 sachets per child treated. Among children admitted with MUAC < 115 mm or edema, 87% recovered with a mean length of stay of 55 days and consuming an average of 96 RUTF sachets. The recovery in all sub-groups studied exceeded 85%. Treatment by CHWs resulted in a similar (94%) recovery to treatment by formal healthcare workers (92%). The simplified, combined protocol resulted in high recovery and low RUTF consumption per child treated and can safely be adopted by CHWs to provide treatment at the community level.

Indexed as

MalnutritionChildCohort StudiesEdemaHumansMaliObservational Studies as TopicTreatment Outcomeacute malnutritioncombined protocolcommunity-based management of acute malnutritionmid-upper-arm circumferencesimplified protocolwasting

Identifiers

PMID36432609
PMCPMC9699530

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.