ReviewNutrients2022
Association of Zinc with Anemia.
Review in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07140874 (Evaluation of Supplemental Zinc as an Adjunct to Prolong the Duration of Benefit After Botulinum Toxin Injections in Subjects With Cervical Dystonia), which is not on this map. Cited by 46 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of Supplemental Zinc as an Adjunct to Prolong the Duration of Benefit After Botulinum Toxin Injections in Subjects With Cervical Dystonia
Who cites it
46 citing papers in PubMed, 84 citations in OpenAlex.
- Zinc deficiency and antihypertensive treatment intensity in patients initiating dialysis: a cross-sectional analysis from the Jikei hemodialysis and peritoneal dialysis study (JHPS).Clinical and experimental nephrology · 2026Article
- Associations between metals and anemia indicator: mixed exposure effects and mediation analysis.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026Article
- Oyster-derived Zinc Exhibits Superior Anti-anemic Efficacy and Bioavailability Compared with Conventional Zinc Supplements.Biological trace element research · 2026Article
- The relationship between serum zinc level and prognosis of non-dialysis CKD patients.BMC nephrology · 2026Article
- Plasma Multi-Metal Exposure, Renal Function, and Anemia Risk in Rural China: The Mediating Role of Serum Creatinine.Biological trace element research · 2026Article
- Defining Reference Intervals for Complete Blood Count and Micronutrient Parameters in Urban Bangladeshi Population.Biomolecules · 2026Article
- The hazards of metal exposure mediated by crops to human health from perspective of environmental health and control strategies.iScience · 2026Review
- Impact of the COVID-19 pandemic on growth, nutrition and immune function in infants and toddlers.Public health nutrition · 2026Article
- Mineral-Specific Anemia Risk Patterns among Elderly Chinese Adults: Findings from A Cross-Sectional Study.Biological trace element research · 2026Article
- Zinc deficiency is associated with erythropoietin-stimulating agents hyporesponsive anemia in peritoneal dialysis patients: a cross-sectional study.Clinical and experimental nephrology · 2026Article
- Nutrigenomic profiling identifies ZIP10 (Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Correlative imaging reveals metal dyshomeostasis and altered zinc coordination environments in a pre-clinical Type 2 diabetes model.Metallomics : integrated biometal science · 2026Article
- Article
- Current perspectives and updates on transfusion strategies in critically ill anemic patients.Frontiers in medicine · 2026Review
- Prevalence and determinants of anaemia among university students: a gender-based analysis.Frontiers in public health · 2026Article
- The Role of Micronutrients in Atherosclerosis: Mechanisms and Clinical Application.Journal of cellular and molecular medicine · 2025Review
- Vitamin A, Vitamin D, Iron, and Zinc in Relation to Anemia Risk: Observational Evidence and Mendelian Randomization.Nutrients · 2025Observational
- Assessment and management of magnesium and trace element status in children with CKD stages 2-5, on dialysis and post-transplantation: Clinical practice points from the Pediatric Renal Nutrition Taskforce.Pediatric nephrology (Berlin, Germany) · 2025Review
- Dietary coated copper and zinc improved growth performance by modulating immune responses and fecal microbiota of weaned pigs.Journal of animal science and technology · 2025Article
- Malaria-induced dysregulation of selected micronutrients (Ca, Mg, Na, K, Zn, Fe, Co) and plasma free amino acids; implications for pathogenesis and host immunity in a Nigerian population.Parasite epidemiology and control · 2025Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Zinc is an essential trace element, and anemia is the most common blood disorder. The association of zinc with anemia may be divided into three major forms: (1) zinc deficiency contributing to anemia, (2) excess intake of zinc leading to anemia, and (3) anemia leading to abnormal blood-zinc levels in the body. In most cases, zinc deficiency coexists with iron deficiency, especially in pregnant women and preschool-age children. To a lesser extent, zinc deficiency may cooperate with other factors to lead to anemia. It seems that zinc deficiency alone does not result in anemia and that it may need to cooperate with other factors to lead to anemia. Excess intake of zinc is rare. However, excess intake of zinc interferes with the uptake of copper and results in copper deficiency that leads to anemia. Animal model studies indicate that in anemia, zinc is redistributed from plasma and bones to the bone marrow to produce new red blood cells. Inadequate zinc status (zinc deficiency or excess) could have effects on anemia; at the same time, anemia could render abnormal zinc status in the body. In handling anemia, zinc status needs to be observed carefully, and supplementation with zinc may have preventive and curative effects.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.