Evidence map›Paper›PMID 36432592›Full record

ArticleNutrients2022

Are Undernutrition and Obesity Associated with Post-Discharge Mortality and Re-Hospitalization after Hospitalization with Community-Acquired Pneumonia?

Maria H Hegelund, Camilla K Ryrsø, Christian Ritz, Arnold M Dungu, Adin Sejdic, Andreas V Jensen, Nikita M Hansen, Christian Mølgaard, Rikke Krogh-Madsen, Birgitte Lindegaard and 1 more

Abstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Effect of Exercise Training on Prognosis in Community-acquired Pneumonia: A Randomized Controlled Trial.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
    Trial
  3. Article
  4. Review
  5. Observational
  6. Article
  7. Article
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  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Maria H HegelundDepartment of Pulmonary and Infectious Diseases, Copenhagen University Hospital-North Zealand, 3400 Hillerød, Denmark.ORCID 0000-0001-6287-1619
Camilla K RyrsøDepartment of Pulmonary and Infectious Diseases, Copenhagen University Hospital-North Zealand, 3400 Hillerød, Denmark.ORCID 0000-0002-8059-7331
Christian RitzThe Research Department for Health and Morbidity in the Population, National Institute of Public Health, University of Southern Denmark, 1455 Copenhagen, Denmark.ORCID 0000-0002-5095-0624
Arnold M DunguDepartment of Pulmonary and Infectious Diseases, Copenhagen University Hospital-North Zealand, 3400 Hillerød, Denmark.
Adin SejdicDepartment of Pulmonary and Infectious Diseases, Copenhagen University Hospital-North Zealand, 3400 Hillerød, Denmark.
Andreas V JensenDepartment of Pulmonary and Infectious Diseases, Copenhagen University Hospital-North Zealand, 3400 Hillerød, Denmark.
Nikita M HansenDepartment of Nephrology, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark.ORCID 0000-0002-6009-5617
Christian MølgaardDepartment of Nutrition, Exercise and Sports, University of Copenhagen, 1958 Frederiksberg, Denmark.
Rikke Krogh-MadsenCentre for Physical Activity Research, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark.ORCID 0000-0003-4914-2715
Birgitte LindegaardDepartment of Pulmonary and Infectious Diseases, Copenhagen University Hospital-North Zealand, 3400 Hillerød, Denmark.
Daniel Faurholt-JepsenDepartment of Infectious Diseases, Copenhagen University Hospital-Rigshospitalet, 2100 Copenhagen, Denmark.ORCID 0000-0001-8561-0155

Funding

Helsefonden 19-B-0155Research Council at Copenhagen University Hospital - North Zealand - Denmark None
6 · The paper itself

Abstract

Undernutrition is associated with increased mortality after hospitalization with community-acquired pneumonia (CAP), whereas obesity is associated with decreased mortality in most studies. We aimed to determine whether undernutrition and obesity are associated with increased risk of re-hospitalization and post-discharge mortality after hospitalization. This study was nested within the Surviving Pneumonia cohort, which is a prospective cohort of adults hospitalized with CAP. Patients were categorized as undernourished, well-nourished, overweight, or obese. Undernutrition was based on diagnostic criteria by the European Society for Clinical Nutrition and Metabolism. Risk of mortality was investigated using multivariate logistic regression and re-hospitalization with competing risk Cox regression where death was the competing event. Compared to well-nourished patients, undernourished patients had a higher risk of 90-day (OR 3.0, 95% CI 1.0; 21.4) mortality, but a similar 30-day and 180-day mortality risk. Obese patients had a similar re-hospitalization and mortality risk as well-nourished patients. In conclusion, among patients with CAP, undernutrition was associated with increased risk of mortality. Undernourished patients are high-risk patients, and our results indicate that in-hospital screening of undernutrition should be implemented to identify patients at mortality risk. Studies are required to investigate whether nutritional therapy after hospitalization with CAP would improve survival.

Indexed as

Community-Acquired InfectionsMalnutritionPneumoniaAdultAftercareHospitalizationHumansObesityPatient DischargeProspective Studiescommunity-acquired pneumoniamortalityobesityre-hospitalizationundernutrition

Identifiers

PMID36432592
PMCPMC9697837

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.