ReviewNutrients2022
Physiological Alterations in Relation to Space Flight: The Role of Nutrition.
Review in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Neural Vision Restoration in Ophthalmology.Annals of biomedical engineering · 2026Review
- Vascular and musculoskeletal interactions: structure, function, and therapeutic strategies for sarcopenia and osteoporosis.MedScience · 2026Review
- Microgravity as a translational model for metabolic dysfunction: implications for obesity, insulin resistance, steatotic liver and pancreatic diseases.Frontiers in endocrinology · 2026Review
- Impact of spaceflight on endocrine, metabolic and kidney function: current evidence, open issues, and potential countermeasures.BMC biology · 2025Review
- Spaceflight Standard Measures is a multidisciplinary study that systematically monitors risks to astronaut health and performance.NPJ microgravity · 2025Review
- Modeling Glioblastoma with Brain Organoids: New Frontiers in Oncology and Space Research.International journal of molecular sciences · 2025Review
- Review
- Blood flow restriction training in microgravity: a review of multisystem physiological benefits and implementation challenges for long-duration space missions.NPJ microgravity · 2025Review
- Ankle Somatosensation and Lower-Limb Neuromuscular Function on a Lunar Gravity Analogue.Brain sciences · 2025Article
- Bone-brain interaction: mechanisms and potential intervention strategies of biomaterials.Bone research · 2025Review
- Combined Effects of Microgravity and Chronic Low-Dose Gamma Radiation onPlants (Basel, Switzerland) · 2024Article
- Salidroside alleviates simulated microgravity-induced bone loss by activating the Nrf2/HO-1 pathway.Journal of orthopaedic surgery and research · 2024Article
- Cardiovascular effects of long-duration space flight.Health science reports · 2024Review
- Thiamine-modified metabolic reprogramming of human pluripotent stem cell-derived cardiomyocyte under space microgravity.Signal transduction and targeted therapy · 2024Article
- Navigating the Unknown: A Comprehensive Review of Spaceflight-Associated Neuro-Ocular Syndrome.Cureus · 2024Review
- Harnessing Passive Pulsatile Shear Stress for Alzheimer's Disease Prevention and Intervention.Journal of Alzheimer's disease : JAD · 2024Review
- Omega-3-Enriched Diet Improves Metabolic Profile in Prdx6-Deficient Mice Exposed to Microgravity.Life (Basel, Switzerland) · 2023Article
- Vitamin C inhibits the growth of colorectal cancer cell HCT116 and reverses the glucose-induced oncogenic effect by downregulating the Warburg effect.Medical oncology (Northwood, London, England) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Astronauts exhibit several pathophysiological changes due to a variety of stressors related to the space environment, including microgravity, space radiation, isolation, and confinement. Space motion sickness, bone and muscle mass loss, cardiovascular deconditioning and neuro-ocular syndrome are some of the spaceflight-induced effects on human health. Optimal nutrition is of the utmost importance, and-in combination with other measures, such as physical activity and pharmacological treatment-has a key role in mitigating many of the above conditions, including bone and muscle mass loss. Since the beginning of human space exploration, space food has not fully covered astronauts' needs. They often suffer from menu fatigue and present unintentional weight loss, which leads to further alterations. The purpose of this review was to explore the role of nutrition in relation to the pathophysiological effects of spaceflight on the human body.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.