Evidence map›Paper›PMID 36432547›Full record

ArticleNutrients2022

Inadequate Choline Intake in Pregnant Women in Germany.

Merle Roeren, Anna Kordowski, Christian Sina, Martin Smollich

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Assessment of vitamin A, vitamin BEuropean journal of nutrition · 2025
    Trial
  3. Article
  4. Observational
  5. Article
  6. Article
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  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Merle RoerenInstitute of Nutritional Medicine, University Hospital Schleswig-Holstein, Campus Luebeck, University of Luebeck, 23538 Luebeck, Germany.
Anna KordowskiInstitute of Nutritional Medicine, University Hospital Schleswig-Holstein, Campus Luebeck, University of Luebeck, 23538 Luebeck, Germany.ORCID 0000-0003-1735-2793
Christian SinaInstitute of Nutritional Medicine, University Hospital Schleswig-Holstein, Campus Luebeck, University of Luebeck, 23538 Luebeck, Germany.
Martin SmollichInstitute of Nutritional Medicine, University Hospital Schleswig-Holstein, Campus Luebeck, University of Luebeck, 23538 Luebeck, Germany.ORCID 0000-0003-1297-8535
University Hospital Schleswig-Holstein · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Choline is an essential nutrient that is involved in various developmental processes during pregnancy. While the general adequate choline intake (AI) for adults has been set at 400 mg/day by the European Food Safety Authority (EFSA), an AI of 480 mg/day has been derived for pregnant women. To date, the choline intake of pregnant women in Germany has not been investigated yet. Therefore, in this survey, the total choline intake from dietary and supplementary sources in pregnant women was estimated using an online questionnaire. A total of 516 pregnant women participated in the survey, of which 283 met the inclusion criteria (13 to 41 weeks of gestational age, 19−45 years). 224 (79%) of the participants followed an omnivorous diet, 59 (21%) were vegetarian or vegan. Median choline intake was 260.4 (±141.4) mg/day, and only 19 women (7%) achieved the adequate choline intake. The median choline intake of omnivores was significantly higher than that of vegetarians/vegans (269.5 ± 141.5 mg/day vs. 205.2 ± 101.2 mg/day; p < 0.0001). 5% (13/283) of pregnant women took choline-containing dietary supplements. In these women, dietary supplements provided 19% of the total choline intake. Due to the importance of choline for the developmental processes during pregnancy, the study results prove the urgent need for an improved choline supply for pregnant women.

Indexed as

CholinePregnant PeopleAdultFemaleGermanyHumansMiddle AgedPregnancyVegansVegetariansYoung AdultCholineadequate intakecholineomnivorouspregnancyveganvegetarian

Identifiers

PMID36432547
PMCPMC9696170
OpenAlexW4309456307

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.