Evidence map›Paper›PMID 36432501›Full record

ArticleNutrients2022

The Complex of Phycobiliproteins, Fucoxanthin, and Krill Oil Ameliorates Obesity through Modulation of Lipid Metabolism and Antioxidants in Obese Rats.

Xi Qiang, Chuanlong Guo, Wenhui Gu, Yuling Song, Yuhong Zhang, Xiangzhong Gong, Lijun Wang, Guangce Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Metabolites · 2025
    Article
  2. Article
  3. Review
  4. Effect ofInternational journal of molecular sciences · 2024
    Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Xi QiangCAS and Shandong Province Key Laboratory of Experimental Marine Biology, Center for Ocean Mega-Science, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China.
Chuanlong GuoDepartment of Pharmacy, College of Chemical Engineering, Qingdao University of Science and Technology, Qingdao 266042, China.
Wenhui GuCAS and Shandong Province Key Laboratory of Experimental Marine Biology, Center for Ocean Mega-Science, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China.
Yuling SongCAS and Shandong Province Key Laboratory of Experimental Marine Biology, Center for Ocean Mega-Science, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China.
Yuhong ZhangQingdao Shinan District Center for Disease Control & Prevention, Qingdao 266072, China.
Xiangzhong GongCollege of Marine Life Sciences, Ocean University of China, Qingdao 266003, China.
Lijun WangCAS and Shandong Province Key Laboratory of Experimental Marine Biology, Center for Ocean Mega-Science, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China.ORCID 0000-0002-0462-7033
Guangce WangCAS and Shandong Province Key Laboratory of Experimental Marine Biology, Center for Ocean Mega-Science, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China.
Chinese Academy of Sciences · CNOcean University of China · CNQingdao Municipal Center for Disease Control and Prevention · CNQingdao University of Science and Technology · CN

Funding

Major Scientific and Technological Innovation Projects of Shandong Province No. 2019JZZY010815Ministry of Agriculture and Rural Affairs of the People's Republic of China CARS-50Nantong Municipal Science and Technology Planning Project MS22021017the National Key R&D Program of China No. 2018YFD0901500the Research Fund for the Taishan Scholar Project of Shandong Province tspd 20210316
6 · The paper itself

Abstract

Phycobiliproteins, fucoxanthin, and krill oil are natural marine products with excellent activities. In the study, we prepared the complex of phycobiliproteins, fucoxanthin, and krill oil (PFK) and assessed the anti-obesity, lipid-lowering, and antioxidant activities in high-fat diet rats. The results showed that the rats significantly and safely reduced body weight gain and regulated serum biochemical parameters at 50 mg/kg phycobiliproteins, 10 mg/kg fucoxanthin, and 100 mg/kg krill oil. Furthermore, the molecular mechanism study suggested that the complex of PFK confined the enzyme activities of lipid synthesis and enhanced antioxidant activity to improve obesity indirectly. The conclusions demonstrated that the complex of PFK has potent anti-obesity and hypolipidemic effects which have potential use as a natural and healthy food and medicine for anti-obesity and lowering blood lipids in the future.

Indexed as

EuphausiaceaLipid MetabolismAnimalsAntioxidantsLipidsObesityOilsPhycobiliproteinsRatsXanthophyllsAntioxidantsfucoxanthinLipidsOilsPhycobiliproteinsXanthophyllsfucoxanthinkrill oillipid metabolismobesityphycobiliproteins

Identifiers

PMID36432501
PMCPMC9693846
OpenAlexW4309026042

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.