Evidence map›Paper›PMID 36432472›Full record

SynthesisNutrients2022

Dietary Potassium Intake and Risk of Diabetes: A Systematic Review and Meta-Analysis of Prospective Studies.

Lanfranco D'Elia, Maria Masulli, Francesco P Cappuccio, Aquilino F Zarrella, Pasquale Strazzullo, Ferruccio Galletti

Registry-linked trialOpen access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05994313 (STARchy Staples), which is not on this map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05994313 nacompletednot on this mapstarted 2023, after this paper: background citation

STARchy Staples: a Randomised Controlled Trial on Cardiometabolic Health

TypeinterventionalSponsorKing's College LondonRan2023 to 2025Enrolled71ConditionsCardiometabolic HealthArmsHabitual potato consumption, Habitual non-nutrient-dense staple consumption
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. "Minimal-Advice" on Salt Intake: Results of a Multicentre Pilot Randomised Controlled Trial on Hypertensive Patients.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2025
    Trial
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Low Potassium Intake: A Common Risk Factor for Nephrolithiasis in Patients with High Blood Pressure.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2023
    Article
  13. Nutritional Composition of Hass Avocado Pulp.Foods (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Lanfranco D'EliaDepartment of Clinical Medicine and Surgery, "Federico II" University of Naples Medical School, 80131 Naples, Italy.ORCID 0000-0002-1782-0211
Maria MasulliDepartment of Clinical Medicine and Surgery, "Federico II" University of Naples Medical School, 80131 Naples, Italy.
Francesco P CappuccioWorld Health Organization Collaborating Centre for Nutrition, Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK.ORCID 0000-0002-7842-5493
Aquilino F ZarrellaDepartment of Clinical Medicine and Surgery, "Federico II" University of Naples Medical School, 80131 Naples, Italy.ORCID 0000-0002-7720-6870
Pasquale StrazzulloDepartment of Clinical Medicine and Surgery, "Federico II" University of Naples Medical School, 80131 Naples, Italy.
Ferruccio GallettiDepartment of Clinical Medicine and Surgery, "Federico II" University of Naples Medical School, 80131 Naples, Italy.
University Hospital Coventry · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Dietary potassium intake is positively associated with reduction of cardiovascular risk. Several data are available on the relationship between dietary potassium intake, diabetes risk and glucose metabolism, but with inconsistent results. Therefore, we performed a meta-analysis of the prospective studies that explored the effect of dietary potassium intake on the risk of diabetes to overcome these limitations. (2) Methods: A random-effects dose-response meta-analysis was carried out for prospective studies. A potential non-linear relation was investigated using restricted cubic splines. (3) Results: A total of seven prospective studies met the inclusion criteria. Dose-response analysis detected a non-linear relationship between dietary potassium intake and diabetes risk, with significant inverse association starting from 2900 mg/day by questionnaire and between 2000 and 5000 mg/day by urinary excretion. There was high heterogeneity among studies, but no evidence of publication bias was found. (4) Conclusions: The results of this meta-analysis indicate that habitual dietary potassium consumption is associated with risk of diabetes by a non-linear dose-response relationship. The beneficial threshold found supports the campaigns in favour of an increase in dietary potassium intake to reduce the risk of morbidity and mortality. Further studies should be carried out to explore this topic.

Indexed as

Diabetes MellitusPotassium, DietaryHumansProspective StudiesRisk FactorsSurveys and QuestionnairesPotassium, Dietarydiabetesdietary potassiumglucose metabolismmeta-analysispotassium consumptionpotassium intake

Identifiers

PMID36432472
PMCPMC9697076
OpenAlexW4309004027

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.