Evidence map›Paper›PMID 36432410›Full record

ReviewNutrients2022

Prospects of Probiotic Adjuvant Drugs in Clinical Treatment.

Zhongyue Ren, Yan Hong, Yalan Huo, Lingling Peng, Huihui Lv, Jiahui Chen, Zhihua Wu, Cuixiang Wan

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Zhongyue RenState Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China.
Yan HongJiangxi Institution for Drug Control, Nanchang 330024, China.
Yalan HuoDepartment of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University, 575 W Stadium Ave., West Lafayette, IN 47907, USA.
Lingling PengState Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China.
Huihui LvState Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China.
Jiahui ChenState Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China.
Zhihua WuState Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China.ORCID 0000-0001-5988-3643
Cuixiang WanState Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China.
Nanchang University · CNJiang Xi Institute for Drug Control · CNPurdue University West Lafayette · US

Funding

National Natural Science Foundation of China 81760102National Nature Science Foundation of Jiangxi Province 20212BAB205027
6 · The paper itself

Abstract

In modern society, where new diseases and viruses are constantly emerging, drugs are still the most important means of resistance. However, adverse effects and diminished efficacy remain the leading cause of treatment failure and a major determinant of impaired health-related quality of life for patients. Clinical studies have shown that the disturbance of the gut microbial structure plays a crucial role in the toxic and side effects of drugs. It is well known that probiotics have the ability to maintain the balance of intestinal microecology, which implies their potential as an adjunct to prevent and alleviate the adverse reactions of drugs and to make medicines play a better role. In addition, in the past decade, probiotics have been found to have excellent prevention and alleviation effects in drug toxicity side effects, such as liver injury. In this review, we summarize the development history of probiotics, discuss the impact on drug side effects of probiotics, and propose the underlying mechanisms. Probiotics will be a new star in the world of complementary medicine.

Indexed as

Drug-Related Side Effects and Adverse ReactionsProbioticsAnalgesicsHumansQuality of LifeTreatment FailureAnalgesicscomplementary medicinedrug side effectsintestinal floraprobiotics

Identifiers

PMID36432410
PMCPMC9697729
OpenAlexW4308866277

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.