Evidence map›Paper›PMID 36432124›Full record

ArticleMolecules (Basel, Switzerland)2022

Encapsulation of Vitamin C by Glycerol-Derived Dendrimers, Their Interaction with Biomimetic Models of

Katia Bacha, Catherine Chemotti, Jean-Claude Monboisse, Anthony Robert, Aurélien L Furlan, Willy Smeralda, Christian Damblon, Julien Estager, Sylvie Brassart-Pasco, Jean-Pierre Mbakidi and 3 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Katia BachaMolecular Chemistry Reims Institute UMR CNRS 7312, Reims Champagne-Ardenne University, Boîte n° 44, B.P. 1039, F-51687 Reims, France.ORCID 0000-0001-9949-9814
Catherine ChemottiLaboratory of Molecular Biophysics at Interfaces (LBMI), Gembloux Agro-Bio Tech-University of Liege, Passage des Déportés, 2 B-5030 Gembloux, Belgium.
Jean-Claude MonboisseLaboratoire de Biochimie Médicale et de Biologie Moléculaire, UMR CNRS/URCA 7369 (MEDyC), UFR Médecine, Reims Champagne Ardenne University, 51 Rue Cognacq Jay, F-51095 Reims, France.
Anthony RobertMolecular Chemistry Reims Institute UMR CNRS 7312, Reims Champagne-Ardenne University, Boîte n° 44, B.P. 1039, F-51687 Reims, France.
Aurélien L FurlanLaboratory of Molecular Biophysics at Interfaces (LBMI), Gembloux Agro-Bio Tech-University of Liege, Passage des Déportés, 2 B-5030 Gembloux, Belgium.
Willy SmeraldaLaboratory of Molecular Biophysics at Interfaces (LBMI), Gembloux Agro-Bio Tech-University of Liege, Passage des Déportés, 2 B-5030 Gembloux, Belgium.ORCID 0000-0001-6772-8993
Christian DamblonStructural Biological Chemistry Laboratory, MolSys Research Unity, University of Liege, 11, Allée du six Août, 4000 Liège, Belgium.
Julien EstagerCertech, Rue Jules Bordet, 45-Zone Industrielle C, B 7180 Seneffe, Belgium.
Sylvie Brassart-PascoLaboratoire de Biochimie Médicale et de Biologie Moléculaire, UMR CNRS/URCA 7369 (MEDyC), UFR Médecine, Reims Champagne Ardenne University, 51 Rue Cognacq Jay, F-51095 Reims, France.ORCID 0000-0002-1340-7868
Jean-Pierre MbakidiMolecular Chemistry Reims Institute UMR CNRS 7312, Reims Champagne-Ardenne University, Boîte n° 44, B.P. 1039, F-51687 Reims, France.
Jelena PršićLaboratory of Molecular Biophysics at Interfaces (LBMI), Gembloux Agro-Bio Tech-University of Liege, Passage des Déportés, 2 B-5030 Gembloux, Belgium.ORCID 0000-0002-3943-7491
Sandrine BouquillonMolecular Chemistry Reims Institute UMR CNRS 7312, Reims Champagne-Ardenne University, Boîte n° 44, B.P. 1039, F-51687 Reims, France.
Magali DeleuLaboratory of Molecular Biophysics at Interfaces (LBMI), Gembloux Agro-Bio Tech-University of Liege, Passage des Déportés, 2 B-5030 Gembloux, Belgium.ORCID 0000-0001-8255-2965
Centre National de la Recherche Scientifique · FRUniversity of Liège · BECentre of Technological Resources in Chemistry · BE

Funding

France-Wallonie-Vlaanderen Interreg 2014-2020 program project number 1.1.338 INTICOSM
6 · The paper itself

Abstract

Vitamin C is one of the most sensitive cosmetic active ingredients. To avoid its degradation, its encapsulation into biobased carriers such as dendrimers is one alternative of interest. In this work, we wanted to evaluate the potential of two biobased glycerodendrimer families (GlyceroDendrimers-Poly(AmidoAmine) (GD-PAMAMs) or GlyceroDendrimers-Poly(Propylene Imine) (GD-PPIs)) as a vitamin C carrier for topical application. The higher encapsulation capacity of GD-PAMAM-3 compared to commercial PAMAM-3 and different GD-PPIs, and its absence of cytotoxicity towards dermal cells, make it a good candidate. Investigation of its mechanism of action was done by using two kinds of biomimetic models of

Indexed as

DendrimersAscorbic AcidBiomimeticsGlycerolHumansLipidsLiposomesVitaminsAscorbic AcidDendrimersGlycerolLipidsLiposomesVitaminscytotoxicitydendrimersencapsulationglycerolliposomesmembrane interactionsstratum corneum biomimetic membranesvitamin C

Identifiers

PMID36432124
PMCPMC9698622
OpenAlexW4309721567

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.