Evidence map›Paper›PMID 36431932›Full record

ReviewMolecules (Basel, Switzerland)2022

Effects of Natural Polyphenols on Skin and Hair Health: A Review.

Mang Sun, Ya Deng, Xining Cao, Lu Xiao, Qian Ding, Fuqing Luo, Peng Huang, Yuanyuan Gao, Mengqi Liu, Hengguang Zhao

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
10.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. FePlants (Basel, Switzerland) · 2026
    Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Chemical Profile and Promising Applications ofAntioxidants (Basel, Switzerland) · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Antibiotics (Basel, Switzerland) · 2024
    Review
  17. Biological Activity of Horehound (Pharmaceuticals (Basel, Switzerland) · 2024
    Article
  18. Article
  19. Article
  20. The Promising Role of Polyphenols in Skin Disorders.Molecules (Basel, Switzerland) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Mang SunDepartment of Dermatology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.
Ya DengDepartment of Dermatology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.
Xining CaoDepartment of Dermatology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.
Lu XiaoDepartment of Dermatology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.
Qian DingDepartment of Dermatology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.
Fuqing LuoDepartment of Dermatology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.
Peng HuangDepartment of Dermatology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.
Yuanyuan GaoDepartment of Dermatology, Daping Hospital, The Army Medical University, Chongqing 400042, China.
Mengqi LiuBioengineering College, Chongqing University, Chongqing 400030, China.
Hengguang ZhaoDepartment of Dermatology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.ORCID 0000-0003-2225-7651
Dalian Medical University · CNArmy Medical University · CNChongqing University · CN

Funding

National Natural Science Foundation of China 82173440
6 · The paper itself

Abstract

The skin is the largest organ of the body and plays multiple essential roles, ranging from regulating temperature, preventing infections, to ultimately affecting human health. A hair follicle is a complex cutaneous appendage. Skin diseases and hair loss have a significant effect on the quality of life and psychosocial adjustment of individuals. However, the available traditional drugs for treating skin and hair diseases may have some insufficiencies; therefore, a growing number of researchers are interested in natural materials that could achieve satisfactory results and minimize adverse effects. Natural polyphenols, named for the multiple phenolic hydroxyl groups in their structures, are promising candidates and continue to be of scientific interest due to their multifunctional biological properties and safety. Polyphenols have a wide range of pharmacological effects. In addition to the most common effect, antioxidation, polyphenols have anti-inflammatory, bacteriostatic, antitumor, and other biological effects associated with reduced risk of a number of chronic diseases. Various polyphenols have also shown efficacy against different types of skin and hair diseases, both in vitro and in vivo, via different mechanisms. Thus, this paper reviews the research progress in natural polyphenols for the protection of skin and hair health, especially focusing on their potential therapeutic mechanisms against skin and hair disorders. A deep understanding of natural polyphenols provides a new perspective for the safe treatment of skin diseases and hair loss.

Indexed as

PolyphenolsSkin DiseasesAlopeciaHair FollicleHumansQuality of LifePolyphenolshairhuman healthpolyphenolsskin

Identifiers

PMID36431932
PMCPMC9695112
OpenAlexW4308909324

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.