Evidence map›Paper›PMID 36431900›Full record

ArticleMolecules (Basel, Switzerland)2022

Insights into Antimalarial Activity of

Jiri Kos, Gilles Degotte, Dominika Pindjakova, Tomas Strharsky, Timotej Jankech, Tomas Gonec, Pierre Francotte, Michel Frederich, Josef Jampilek

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Crystal structure and Hirshfeld surface studies of 4-bromo-2-chloro-phenyl (2Acta crystallographica. Section E, Crystallographic communications · 2025
    Article
  2. Crystal structure and Hirshfeld surface analysis of 4-bromo-2-chloro-phenyl (Acta crystallographica. Section E, Crystallographic communications · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 4 countries.

Jiri KosDepartment of Biochemistry, Faculty of Medicine, Masaryk University, Kamenice 5, 62500 Brno, Czech Republic.ORCID 0000-0002-3589-4361
Gilles DegotteI2BM, Department of Molecular Chemistry, University Grenoble-Alpes, Rue de la Chimie 570, 38610 Gieres, France.ORCID 0000-0001-6318-4626
Dominika PindjakovaDepartment of Analytical Chemistry, Faculty of Natural Sciences, Comenius University, Ilkovicova 6, 84215 Bratislava, Slovakia.
Tomas StrharskyDepartment of Chemical Drugs, Faculty of Pharmacy, Masaryk University, Palackeho 1946/1, 61200 Brno, Czech Republic.ORCID 0000-0001-9291-5424
Timotej JankechDepartment of Analytical Chemistry, Faculty of Natural Sciences, Comenius University, Ilkovicova 6, 84215 Bratislava, Slovakia.ORCID 0000-0001-6685-877X
Tomas GonecDepartment of Chemical Drugs, Faculty of Pharmacy, Masaryk University, Palackeho 1946/1, 61200 Brno, Czech Republic.ORCID 0000-0003-3712-8641
Pierre FrancotteLaboratory of Medicinal Chemistry, CIRM, Department of Pharmacy, University of Liege, Avenue Hippocrate 15, 4000 Liege, Belgium.
Michel FrederichLaboratory of Pharmacognosy, CIRM, Department of Pharmacy, University of Liege, Avenue Hippocrate 15, 4000 Liege, Belgium.ORCID 0000-0002-0770-9990
Josef JampilekDepartment of Analytical Chemistry, Faculty of Natural Sciences, Comenius University, Ilkovicova 6, 84215 Bratislava, Slovakia.ORCID 0000-0003-2003-9052
Masaryk University · CZComenius University Bratislava · SKUniversity of Liège · BEPalacký University Olomouc · CZUniversité Grenoble Alpes · FR

Funding

FRS-FNRS FC23283Operation Program of Integrated Infrastructure for the 290 project, UpScale of Comenius University Capacities and Competence in Research, Development 291 and Innovation ITMS2014+: 313021BUZ3
6 · The paper itself

Abstract

Due to the urgent need of innovation in the antimalarial therapeutic arsenal, a series of thirty-seven ring-substituted

Indexed as

AntimalarialsFolic Acid AntagonistsMalaria, FalciparumChloroquineHumansStructure-Activity RelationshipAntimalarialsChloroquineFolic Acid Antagonistsantiplasmodial activitycinnamanilidesPlasmodiumstructure-activity relationships

Identifiers

PMID36431900
PMCPMC9698057
OpenAlexW4309010226

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.