Evidence map›Paper›PMID 36431880›Full record

ArticleMolecules (Basel, Switzerland)2022

Platelet Desialylation Is a Novel Mechanism and Therapeutic Target in

Cheng Zhang, Zhanfeng Zhang, Enyu Liang, Yunlong Gao, Hui Li, Fangfang Xu, Weiye Chen, Ming Liu, Xianzhang Huang

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Timber rattlesnake (Toxicon: X · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Cheng ZhangDepartment of Laboratory Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510120, China.ORCID 0000-0002-4225-3618
Zhanfeng ZhangClinical Laboratory, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
Enyu LiangDepartment of Laboratory Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510120, China.
Yunlong GaoDepartment of Laboratory Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510120, China.ORCID 0000-0002-3336-4201
Hui LiDepartment of Hematology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510120, China.ORCID 0000-0002-9361-7688
Fangfang XuThe Second Clinical School of Medicine Medicial College, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.ORCID 0000-0001-8651-9329
Weiye ChenDepartment of Laboratory Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510120, China.
Ming LiuSchool of Life Sciences, University of Science and Technology of China, Hefei 230027, China.ORCID 0000-0001-7144-2891
Xianzhang HuangDepartment of Laboratory Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510120, China.ORCID 0000-0003-4320-9181
Guangzhou University of Chinese Medicine · CNFirst Affiliated Hospital of Guangzhou University of Chinese Medicine · CNUniversity of Science and Technology of China · CN

Funding

Guangdong Basic and Applied Basic Research Foundation 2019B1515120004Project of administration of Traditional Chinese Medicine of Guangdong Province of China 20202070Science and Technology Planning Project of Guangdong Province 2017ZC0179Science and technology research project of traditional Chinese Medicine of Guangdong Provin-cial Hospital of Chinese Medicine YN2019QL06
6 · The paper itself

Abstract

Venom-induced thrombocytopenia (VIT) is one of the most important hemotoxic effects of a snakebite, which is often associated with venom-induced consumptive coagulopathy (VICC). Refractory thrombocytopenia without significant coagulation abnormalities has also been reported after envenomation by some viperid snakes; however, the mechanisms are not well understood and therapeutic strategies are lacking. Here, we found that patients injured by

Indexed as

AgkistrodonBlood Coagulation DisordersSnake BitesThrombocytopeniaViperidaeAnimalsHumansNeuraminidaseViper VenomsNeuraminidaseViper Venomsdesialylationmacrophageneuraminidaseplateletsnake venomthrombocytopenia

Identifiers

PMID36431880
PMCPMC9695323
OpenAlexW4308970959

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.