Evidence map›Paper›PMID 36431832›Full record

ArticleMolecules (Basel, Switzerland)2022

Insights into the Inhibitory Mechanism of Viniferifuran on Xanthine Oxidase by Multiple Spectroscopic Techniques and Molecular Docking.

Yaxin Yang, Qian Chen, Shiyang Ruan, Junli Ao, Shang-Gao Liao

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yaxin YangSchool of Basic Medicine, Guizhou Medical University, Guian New District, Guizhou 550025, China.
Qian ChenState Key Laboratory of Functions and Applications of Medicinal Plants & School of Pharmacy, Guizhou Medical University, Guian New Area, Guizhou 550025, China.
Shiyang RuanState Key Laboratory of Functions and Applications of Medicinal Plants & School of Pharmacy, Guizhou Medical University, Guian New Area, Guizhou 550025, China.
Junli AoState Key Laboratory of Functions and Applications of Medicinal Plants & School of Pharmacy, Guizhou Medical University, Guian New Area, Guizhou 550025, China.
Shang-Gao LiaoSchool of Basic Medicine, Guizhou Medical University, Guian New District, Guizhou 550025, China.

Funding

Guizhou Science and Technology Department 2020-5006Guizhou Science and Technology Department 2020-6011National Natural Science Foundation of China 81860690
6 · The paper itself

Abstract

Viniferifuran was investigated for its potential to inhibit the activity of xanthine oxidase (XO), a key enzyme catalyzing xanthine to uric acid. An enzyme kinetics analysis showed that viniferifuran possessed a strong inhibition on XO in a typical anti-competitive manner with an IC

Indexed as

Enzyme InhibitorsXanthine OxidaseKineticsMolecular Docking SimulationSpectroscopy, Fourier Transform InfraredEnzyme InhibitorsXanthine Oxidaseinhibition mechanismviniferifuranxanthine oxidase

Identifiers

PMID36431832
PMCPMC9694772

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.