Evidence map›Paper›PMID 36431824›Full record

ArticleMolecules (Basel, Switzerland)2022

Environmentally Sustainable Achiral and Chiral Chromatographic Analysis of Amino Acids in Food Supplements.

Ina Varfaj, Andrea Carotti, Luciano Mangiapelo, Lina Cossignani, Agnese Taticchi, Antonio Macchiarulo, Federica Ianni, Roccaldo Sardella

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ina VarfajDepartment of Pharmaceutical Sciences, University of Perugia, Via Fabretti 48, 06123 Perugia, Italy.ORCID 0000-0003-4905-7115
Andrea CarottiDepartment of Pharmaceutical Sciences, University of Perugia, Via Fabretti 48, 06123 Perugia, Italy.ORCID 0000-0001-6097-3996
Luciano MangiapeloDepartment of Pharmaceutical Sciences, University of Perugia, Via Fabretti 48, 06123 Perugia, Italy.
Lina CossignaniDepartment of Pharmaceutical Sciences, University of Perugia, Via Fabretti 48, 06123 Perugia, Italy.ORCID 0000-0003-3433-604X
Agnese TaticchiDepartment of Agricultural Food and Environmental Sciences, University of Perugia, Via S. Costanzo, 06126 Perugia, Italy.
Antonio MacchiaruloDepartment of Pharmaceutical Sciences, University of Perugia, Via Fabretti 48, 06123 Perugia, Italy.ORCID 0000-0001-9535-4183
Federica IanniDepartment of Pharmaceutical Sciences, University of Perugia, Via Fabretti 48, 06123 Perugia, Italy.ORCID 0000-0003-4293-3100
Roccaldo SardellaDepartment of Pharmaceutical Sciences, University of Perugia, Via Fabretti 48, 06123 Perugia, Italy.ORCID 0000-0001-9856-0230

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two LC methods were developed for the achiral and chiral reversed-phase (RP) analysis of an amino acid (AA) pool in a food supplement, in compliance with the main paradigms of Green Chromatography. A direct achiral ion-pairing RP-HPLC method was optimized under gradient conditions with a water-ethanol (EtOH) eluent containing heptafluorobutyric acid (0.1%,

Indexed as

Amino AcidsAntifibrinolytic AgentsAcetic AcidDietary SupplementsEthanolWaterAcetic AcidAmino AcidsAntifibrinolytic AgentsEthanolWaterenantiorecognition mechanismgreen chromatographyion-pairing agentteicoplanin-based stationary phase

Identifiers

PMID36431824
PMCPMC9697624

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.