Evidence map›Paper›PMID 36431268›Full record

ArticleJournal of clinical medicine2022

Reversible Bronchial Obstruction in Primary Ciliary Dyskinesia.

Hagit Levine, Ophir Bar-On, Vered Nir, Nicole West, Yotam Dizitzer, Huda Mussaffi, Dario Prais

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Pulmonary exacerbations in primary ciliary dyskinesia.European journal of pediatrics · 2026
    Review
  2. Article
  3. Article
  4. Ciliary Function, Antigen Stasis and Asthma.International journal of molecular sciences · 2024
    Review
  5. Antigen stasis and airway nitrosative stress in human primary ciliary dyskinesia.American journal of physiology. Lung cellular and molecular physiology · 2024
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Hagit LevinePulmonary Institute, Schneider Children's Medical Center, Petah-Tikva 49100, Israel.
Ophir Bar-OnPulmonary Institute, Schneider Children's Medical Center, Petah-Tikva 49100, Israel.ORCID 0000-0001-7259-4539
Vered NirDepartment of Pediatrics, Hillel-Yaffe Medical Center, Hadera 3810101, Israel.ORCID 0000-0001-7279-9294
Nicole WestSackler Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.
Yotam DizitzerDepartment of Pediatrics, Schneider Children's Medical Center, Petah-Tikva 4920235, Israel.
Huda MussaffiPulmonary Institute, Schneider Children's Medical Center, Petah-Tikva 49100, Israel.
Dario PraisPulmonary Institute, Schneider Children's Medical Center, Petah-Tikva 49100, Israel.ORCID 0000-0002-4165-0144
Tel Aviv University · ILHillel Yaffe Medical Center · ILSchneider Children's Medical Center · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInhaled bronchodilators are frequently used among patients with primary ciliary dyskinesia (PCD), although neither the effectiveness nor the prevalence of their use is known, due to the paucity of relevant studies.

methodsThis is a retrospective analysis of pre- and post-bronchodilator spirometry results, of patients with PCD from two centers. Correlations were examined of bronchodilator response, with asthma and atopy markers.

resultsOf 115 patients, 46 (40%) completed spirometry pre- and post-bronchodilation. Of these, 26 (56.5%) demonstrated reversible airway obstruction (increase in %FEV

conclusionsMore than half of patients with PCD presented with reversible airway obstruction, without any correlation to markers of personal or familial atopy. Inhaled bronchodilators and corticosteroid therapies are commonly used for treating PCD. Evaluating bronchodilator response should be considered, and its effectiveness should be further studied.

Indexed as

airway hyperreactivityairway obstructionasthmabronchodilatorsinhaled corticosteroidsprimary ciliary dyskinesiaspirometry

Identifiers

PMID36431268
PMCPMC9699262
OpenAlexW4309708514

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.