Evidence map›Paper›PMID 36431240›Full record

ArticleJournal of clinical medicine2022

Preclinical Evaluation of a Novel Small Molecule Inhibitor of LIM Kinases (LIMK) CEL_Amide in Philadelphia-Chromosome Positive (

Jeannig Berrou, Mélanie Dupont, Hanane Djamai, Emilie Adicéam, Véronique Parietti, Anna Kaci, Emmanuelle Clappier, Jean-Michel Cayuela, André Baruchel, Fabrice Paublant and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Regulation and signaling of the LIM domain kinases.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Jeannig BerrouLaboratoire de Transfert des Leucémies, URP-3518, Institut de Recherche Saint-Louis, Université Paris Cité, 75010 Paris, France.
Mélanie DupontLaboratoire de Transfert des Leucémies, URP-3518, Institut de Recherche Saint-Louis, Université Paris Cité, 75010 Paris, France.
Hanane DjamaiLaboratoire de Transfert des Leucémies, URP-3518, Institut de Recherche Saint-Louis, Université Paris Cité, 75010 Paris, France.
Emilie AdicéamLaboratoire de Transfert des Leucémies, URP-3518, Institut de Recherche Saint-Louis, Université Paris Cité, 75010 Paris, France.
Véronique PariettiINSERM/CNRS, US53/UAR2030, Institut de Recherche Saint-Louis, Université Paris Cité, 75010 Paris, France.
Anna KaciLaboratoire de Transfert des Leucémies, URP-3518, Institut de Recherche Saint-Louis, Université Paris Cité, 75010 Paris, France.
Emmanuelle ClappierLaboratory of Hematology, Hôpital Saint-Louis (Assistance Publique-Hôpitaux de Paris and Université Paris Cité), 75010 Paris, France.ORCID 0000-0001-7098-092X
Jean-Michel CayuelaLaboratoire de Transfert des Leucémies, URP-3518, Institut de Recherche Saint-Louis, Université Paris Cité, 75010 Paris, France.
André BaruchelLaboratoire de Transfert des Leucémies, URP-3518, Institut de Recherche Saint-Louis, Université Paris Cité, 75010 Paris, France.
Fabrice PaublantCELLIPSE Company, 38000 Grenoble, France.
Renaud PrudentCELLIPSE Company, 38000 Grenoble, France.
Jacques GhysdaelCNRS UMR3348, INSERM U1278, Institut Curie, Centre Universitaire Bat 110, 91405 Orsay, France.
Claude GardinLaboratoire de Transfert des Leucémies, URP-3518, Institut de Recherche Saint-Louis, Université Paris Cité, 75010 Paris, France.
Hervé DombretLaboratoire de Transfert des Leucémies, URP-3518, Institut de Recherche Saint-Louis, Université Paris Cité, 75010 Paris, France.
Thorsten BraunLaboratoire de Transfert des Leucémies, URP-3518, Institut de Recherche Saint-Louis, Université Paris Cité, 75010 Paris, France.
Université Paris Cité · FRCentre National de la Recherche Scientifique · FR

Funding

CELLIPSE Company
6 · The paper itself

Abstract

Ph+ (

Indexed as

ALLBCR::ABLCEL_AmideLIM kinasetyrosine kinase inhibitors

Identifiers

PMID36431240
PMCPMC9692768
OpenAlexW4309308811

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.