ReviewJournal of clinical medicine2022
Deep Endometriosis and Infertility: What Is the Impact of Surgery?
Review in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- The impact of endometriosis on depressive and anxiety symptoms and quality of life: a systematic review.Frontiers in public health · 2023Pooled it
- Deep Dyspareunia One Year After Nerve-Sparing Endometriosis Surgery: An Observational Study Highlighting Undesirable Outcomes.Journal of personalized medicine · 2026Article
- Integrating IVF and Surgical Management in Endometriosis-Associated Infertility: A Review.Advances in therapy · 2026Review
- Endometriosis and Reproductive Sparing Surgery: A Narrative Review and AGREE II-S-Based Evaluation of International Guidelines.Journal of clinical medicine · 2026Review
- Clinical challenges and therapeutic strategies in women with endometriosis, deep infiltrating endometriosis, and/or adenomyosis undergoing assisted reproductive technologies: a narrative review.Frontiers in reproductive health · 2026Review
- Diagnosis and management of endometriosis-associated infertility Number 4 - 2026.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2026Article
- Infertility management in patients with bowel endometriosis: the current landscape and the promise of randomised trialsFacts, views & vision in ObGyn · 2025Article
- The role of pre-operative gonadotrophin-releasing hormone agonists (GnRHa) on pain, bowel and bladder symptoms in rectovaginal/colorectal endometriosis surgery: a multicenter cohort study.Facts, views & vision in ObGyn · 2025Article
- The impact of surgical intervention on time to conception and obstetric outcomes in women with endometriomas: a retrospective cohort study.BMC pregnancy and childbirth · 2025Article
- A Narrative Review Regarding Implication of Ovarian Endometriomas in Infertility.Life (Basel, Switzerland) · 2025Review
- Female reproductive disease, endometriosis: From inflammation to infertility.Molecules and cells · 2025Review
- Combine Surgery and In Vitro Fertilization (IVF) in Endometriosis-Related Infertility: When and Why.Journal of clinical medicine · 2024Review
- A Systematic Review of Ureteral Reimplantation Techniques in Endometriosis: Laparoscopic Versus Robotic-Assisted Approach.Journal of clinical medicine · 2024Review
- Reproductive surgery remains an essential element of reproductive medicine.Facts, views & vision in ObGyn · 2024Article
- The (cost-) effectiveness Of Surgical excision of Colorectal endometriosis compared to ART treatment trAjectory (TOSCA study) - a study protocol.Reproduction & fertility · 2024Article
- Superficial Peritoneal Endometriosis Vaporization Using a COJournal of clinical medicine · 2024Article
- Spatiotemporal Trends and Age-Period-Cohort Analysis for the Burden of Endometriosis-Related Infertility: An Analysis of the Global Burden of Disease Study 2019.Journal of personalized medicine · 2023Article
- Predictive Model for the Non-Invasive Diagnosis of Endometriosis Based on Clinical Parameters.Journal of clinical medicine · 2023Article
- The Utility of Rectal Water Contrast Transvaginal Ultrasound for Assessment of Deep Bowel Endometriosis.Life (Basel, Switzerland) · 2023Article
- Deep endometriosis. Clinical, histopathological and confocal microscopy correlations in intestinal sites.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologieArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In women with deep endometriosis, the spontaneous fertility rate might range from 2 to 10%. The optimal management of these women is still an area of debate. Therefore, this review aims to explore the literature on the impact of deep endometriosis surgery on reproductive outcomes and pregnancy rates in women with and without prior infertility. A total of 392 articles were identified through database searching. Twenty-three studies were eligible to be included in the review. A total of 1548 women were identified, 814 of whom became pregnant, with a mean pregnancy rate of 52.6% (95% CI 49.7-63%). Our review suggests that surgery may improve fertility outcomes. Due to the variability in the studies, it is impossible to stratify fertility outcomes of surgery by the localization of deep endometriosis. More investigations are needed to determine whether surgical management should be first-intention or limited to the failure of medically assisted reproduction treatment.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.