Evidence map›Paper›PMID 36431013›Full record

ReviewLife (Basel, Switzerland)2022

Functional Insights into Protein Kinase A (PKA) Signaling from

Fereshteh Sadeghian, Perla G Castaneda, Mustafi R Amin, Erin J Cram

Open access · goldAbstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. PES-8 is required for Cytoskeletal Organization and Contractility in thebioRxiv : the preprint server for biology · 2026
    Article
  3. Cortical Somatostatin Neurons Regulate Seizure Susceptibility via MINAR1/Gαs-cAMP Signaling.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. GOA-1 regulates spermathecal transits.microPublication biology · 2025
    Article
  9. Rosmarinic Acid Present inPlants (Basel, Switzerland) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Fereshteh SadeghianDepartment of Bioengineering, Northeastern University, Boston, MA 02115, USA.
Perla G CastanedaDepartment of Biology, Northeastern University, Boston, MA 02115, USA.
Mustafi R AminDepartment of Biology, Northeastern University, Boston, MA 02115, USA.ORCID 0000-0003-0048-9697
Erin J CramDepartment of Biology, Northeastern University, Boston, MA 02115, USA.ORCID 0000-0002-8129-1326
Northeastern University · US

Funding

In vivo analysis of mechanotransductionR01GM110268 · NIGMS · NORTHEASTERN UNIVERSITY · PI CRAM, ERIN JEAN · 2014 to 2023
$2.8M
NIGMS NIH HHS R01 GM110268
6 · The paper itself

Abstract

Protein kinase A (PKA), which regulates a diverse set of biological functions downstream of cyclic AMP (cAMP), is a tetramer consisting of two catalytic subunits (PKA-C) and two regulatory subunits (PKA-R). When cAMP binds the PKA-R subunits, the PKA-C subunits are released and interact with downstream effectors. In

Indexed as

behaviorcalcium signalingcAMPC. elegansphysiologyPKA

Identifiers

PMID36431013
PMCPMC9692727
OpenAlexW4309210947

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.