Early Developmental Changes of Muscle Acetylcholine Receptors Are Little Influenced by Dystrophin Absence in

Marta Morotti, Alessandro Gaeta, Cristina Limatola, Myriam Catalano, Maria Amalia Di Castro, Francesca Grassi

Open access · goldAbstract read

In one paragraph

Article in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.2field-weighted citation impact, top 51% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

Sarcoglycans are enriched at the neuromuscular junction in a nerve-dependent manner.Cell death & disease · 2025
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Marta MorottiDepartment of Physiology and Pharmacology, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0003-1878-0159

Alessandro GaetaDepartment of Physiology and Pharmacology, Sapienza University of Rome, 00185 Rome, Italy.

Cristina LimatolaLaboratory Affiliated to Istituto Pasteur Italia, Department of Physiology and Pharmacology, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0001-7504-8197

Myriam CatalanoDepartment of Physiology and Pharmacology, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0003-4638-9202

Maria Amalia Di CastroDepartment of Physiology and Pharmacology, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0001-7480-1087

Francesca GrassiDepartment of Physiology and Pharmacology, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0002-0169-8397

Sapienza University of Rome · ITIstituto Neurologico Mediterraneo · IT

Funding

Duchenne Parent Project small grant proposal ref. 19.006French Muscular Dystrophy Association 23722Italian Association for Cancer Research IG-23010Ministero della Salute RF-2018-12366215Ministry of Education, Universities and Research PRIN20178L7WRSMinistry of Education, Universities and Research PRIN2020Z73J5ASapienza University of Rome RP1201727EA43399Sapienza University of Rome RP12117A5CD9D9E7

6 · The paper itself

Abstract

Dystrophin is a cytoskeletal protein contributing to the organization of the neuromuscular junction. In Duchenne muscular dystrophy, due to dystrophin absence, the distribution of endplate acetylcholine receptors (AChRs) becomes disorganized. It is still debated whether this is due to the absence of dystrophin or to the repeated damage/regeneration cycles typical of dystrophic muscle. We addressed this controversy studying the endplate in the first 3 postnatal weeks, when muscle damage in dystrophic (

Indexed as

acetylcholine receptorsDuchenne muscular dystrophydystrophic musclemdxneuromuscular junctionpatch clampreceptor clustering

Identifiers

PMID36430996

DOI10.3390/life12111861

PMCPMC9696329

OpenAlexW4308972972

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.