Ononitol Monohydrate-A Glycoside Potentially Inhibit HT-115 Human Colorectal Cancer Cell Proliferation through COX-2/PGE-2 Inflammatory Axis Regulations.

Pandurangan Subash-Babu, Alanoud Aladel, Taghreed N Almanaa, Sahar Abdulaziz AlSedairy, Ali A Alshatwi

Open access · goldAbstract read

In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.8field-weighted citation impact, top 21% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

Special Issue "Dietary Bioactive Components in Inflammatory Bowel Disease".International journal of molecular sciences · 2024
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Pandurangan Subash-BabuCancer Molecular Biology Research Lab, Department of Food Science and Nutrition, College of Food and Agricultural Sciences, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0003-3938-071X

Alanoud AladelCommunity Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0002-1441-607X

Taghreed N AlmanaaDepartment of Botany and Microbiology, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.

Sahar Abdulaziz AlSedairyCancer Molecular Biology Research Lab, Department of Food Science and Nutrition, College of Food and Agricultural Sciences, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0001-5372-5222

Ali A AlshatwiCancer Molecular Biology Research Lab, Department of Food Science and Nutrition, College of Food and Agricultural Sciences, King Saud University, Riyadh 11451, Saudi Arabia.

King Saud University · SA

Funding

Researchers supporting project RSP-2020/178

6 · The paper itself

Abstract

We aimed to inhibit HT-115 human colorectal cancer cell proliferation using ononitol monohydrate (OMH), a bioactive principle isolated from

Indexed as

Cardiac GlycosidesColorectal NeoplasmsCell ProliferationCyclooxygenase 2DinoprostoneGlycosidesHumansTumor Necrosis Factor-alphaTumor Suppressor Protein p53Cardiac GlycosidesCyclooxygenase 2DinoprostoneGlycosidesononitol monohydrateTumor Necrosis Factor-alphaTumor Suppressor Protein p53apoptosiscolorectal cancerCOX-2/PGE-2inflammationononitol monohydrate

Identifiers

PMID36430918

DOI10.3390/ijms232214440

PMCPMC9696259

OpenAlexW4309743883

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.