Evidence map›Paper›PMID 36430898›Full record

ArticleInternational journal of molecular sciences2022

Transcriptome Analysis Reveals Modulation of Human Stem Cells from the Apical Papilla by Species Associated with Dental Root Canal Infection.

Yelyzaveta Razghonova, Valeriia Zymovets, Philip Wadelius, Olena Rakhimova, Lokeshwaran Manoharan, Malin Brundin, Peyman Kelk, Nelly Romani Vestman

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. About a Possible Impact of Endodontic Infections byInternational journal of molecular sciences · 2024
    Review
  8. Article
  9. Article
  10. Review
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Yelyzaveta RazghonovaDepartment of Microbiology, Virology and Biotechnology, Mechnikov National University, 65000 Odesa, Ukraine.
Valeriia ZymovetsDepartment of Odontology, Umeå University, 90187 Umeå, Sweden.
Philip WadeliusDepartment of Endodontics, Region of Västerbotten, 90189 Umeå, Sweden.
Olena RakhimovaDepartment of Odontology, Umeå University, 90187 Umeå, Sweden.ORCID 0000-0002-3536-4467
Lokeshwaran ManoharanNational Bioinformatics Infrastructure Sweden (NBIS), Lund University, 22362 Lund, Sweden.ORCID 0000-0001-9751-5745
Malin BrundinDepartment of Odontology, Umeå University, 90187 Umeå, Sweden.ORCID 0000-0002-8747-3307
Peyman KelkSection for Anatomy, Department of Integrative Medical Biology (IMB), Umeå University, 90187 Umeå, Sweden.ORCID 0000-0003-1594-1738
Nelly Romani VestmanDepartment of Odontology, Umeå University, 90187 Umeå, Sweden.ORCID 0000-0002-5674-8179
Umeå University · SELund University · SEVästerbotten County · SE

Funding

Knut and Alice Wallenberg Foundation 7004361
6 · The paper itself

Abstract

Interaction of oral bacteria with stem cells from the apical papilla (SCAP) can negatively affect the success of regenerative endodontic treatment (RET). Through RNA-seq transcriptomic analysis, we studied the effect of the oral bacteria

Indexed as

Dental Pulp CavityStem CellsCell DifferentiationGene Expression ProfilingHumansIntracellular Signaling Peptides and ProteinsOsteogenesisIntracellular Signaling Peptides and ProteinsWDR5 protein, humandentinogenesisdifferential gene expression analysis (DEG)Enterococcus faecalisFusobacterium nucleatumosteogenesisregenerative endodontic treatment (RET)stem cells from the apical papilla (SCAP)transcriptome analysis

Identifiers

PMID36430898
PMCPMC9695896
OpenAlexW4309720032

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.