Evidence map›Paper›PMID 36430798›Full record

ArticleInternational journal of molecular sciences2022

TERT Promoter Mutations as Simple and Non-Invasive Urinary Biomarkers for the Detection of Urothelial Bladder Cancer in a High-Risk Region.

Hamid Pakmanesh, Omid Anvari, Nathalie Forey, Elisabete Weiderpass, Reza Malekpourafshar, Maryam Iranpour, Armita Shahesmaeili, Nahid Ahmadi, Azam Bazrafshan, Kazem Zendehdel and 7 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 4 countries.

Hamid PakmaneshDepartment of Urology, School of Medicine, Shahid Bahonar Hospital, Kerman University of Medical Sciences, Kerman 7616913555, Iran.ORCID 0000-0001-5534-7042
Omid AnvariDepartment of Urology, School of Medicine, Shahid Bahonar Hospital, Kerman University of Medical Sciences, Kerman 7616913555, Iran.ORCID 0000-0002-7081-5876
Nathalie ForeyInternational Agency for Research on Cancer (IARC), Genomic Epidemiology Branch, 69008 Lyon, France.
Elisabete WeiderpassInternational Agency for Research on Cancer (IARC), Genomic Epidemiology Branch, 69008 Lyon, France.
Reza MalekpourafsharDepartment of Pathology, Pathology and Stem Cell Research Center, Kerman University of Medical Sciences, Kerman 7616913555, Iran.
Maryam IranpourDepartment of Pathology, Pathology and Stem Cell Research Center, Kerman University of Medical Sciences, Kerman 7616913555, Iran.
Armita ShahesmaeiliHIV/STI Surveillance Research Center, and WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman 7616913555, Iran.ORCID 0000-0001-9270-319X
Nahid AhmadiDepartment of Pharmacology and Toxicology, Faculty of Pharmacy, Kerman University of Medical Sciences, Kerman 7616913555, Iran.
Azam BazrafshanHIV/STI Surveillance Research Center, and WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman 7616913555, Iran.
Kazem ZendehdelCancer Research Center, Cancer Institute, Tehran University of Medical Sciences, Tehran 1419733133, Iran.
Caroline KannengiesserDepartment of Genetics, Bichat Claude Bernard Hospital, 75108 Paris, France.ORCID 0000-0003-2155-9383
Ibrahima BaDepartment of Genetics, Bichat Claude Bernard Hospital, 75108 Paris, France.ORCID 0000-0001-5338-3883
James McKayInternational Agency for Research on Cancer (IARC), Genomic Epidemiology Branch, 69008 Lyon, France.
Maria ZverevaChair of Chemistry of Natural Compounds, Department of Chemistry, Lomonosov Moscow State University, 119991 Moscow, Russia.ORCID 0000-0002-7432-1574
Md Ismail HosenDepartment of Biochemistry and Molecular Biology, Faculty of Biological Sciences, University of Dhaka, Dhaka 1000, Bangladesh.ORCID 0000-0003-0862-7206
Mahdi SheikhInternational Agency for Research on Cancer (IARC), Genomic Epidemiology Branch, 69008 Lyon, France.
Florence Le Calvez-KelmInternational Agency for Research on Cancer (IARC), Genomic Epidemiology Branch, 69008 Lyon, France.ORCID 0000-0003-0063-5068
Centre international de recherche sur le cancer · FRKerman University of Medical Sciences · IRShahid Bahonar University of Kerman · IRUniversité Claude Bernard Lyon 1 · FRLomonosov Moscow State University · RUTehran University of Medical Sciences · IRUniversity of Dhaka · BD

Funding

World Health Organization 001
6 · The paper itself

Abstract

Bladder cancer (BC) is the 10th most common cancer in the world. While there are FDA-approved urinary assays to detect BC, none have demonstrated sufficient sensitivity and specificity to be integrated into clinical practice. Telomerase Reverse Transcriptase (

Indexed as

Carcinoma, Transitional CellTelomeraseUrinary Bladder NeoplasmsUrologic NeoplasmsBiomarkers, TumorDNA-Directed RNA PolymerasesHumansMaleMutationNeoplasm Recurrence, LocalBiomarkers, TumorDNA-Directed RNA PolymerasesTelomeraseTERT protein, humanbladder cancernon-invasive detectionopiumsomatic mutationstelomeraseTERT promoter mutationsurinary biomarkers

Identifiers

PMID36430798
PMCPMC9696845
OpenAlexW4309448444

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.