Evidence map›Paper›PMID 36430695›Full record

ArticleInternational journal of molecular sciences2022

Flavones, Flavonols, Lignans, and Caffeic Acid Derivatives from

Karin Jöhrer, Mayra Galarza Pérez, Brigitte Kircher, Serhat Sezai Çiçek

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Targeting Cancer Hallmarks withInternational journal of molecular sciences · 2026
    Review
  2. Review
  3. Article
  4. A Comprehensive Review of the Phenolic Compounds inMolecules (Basel, Switzerland) · 2025
    Review
  5. Review
  6. Cytotoxic Natural Products fromInternational journal of molecular sciences · 2024
    Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Karin JöhrerTyrolean Cancer Research Institute, Innrain 66, 6020 Innsbruck, Austria.ORCID 0000-0002-6400-6175
Mayra Galarza PérezDepartment of Pharmaceutical Biology, Kiel University, Gutenbergstraße 76, 24118 Kiel, Germany.ORCID 0000-0002-6858-6517
Brigitte KircherTyrolean Cancer Research Institute, Innrain 66, 6020 Innsbruck, Austria.ORCID 0000-0003-1624-2664
Serhat Sezai ÇiçekDepartment of Pharmaceutical Biology, Kiel University, Gutenbergstraße 76, 24118 Kiel, Germany.ORCID 0000-0002-3038-8523
Christian-Albrechts-Universität zu Kiel · DEInnsbruck Medical University · ATTyrolean Cancer Research Institute · AT

Funding

Deutsche Forschungsgemeinschaft Open-Access-Publikationskosten
6 · The paper itself

Abstract

Phenolic plant constituents are well known for their health-promoting and cancer chemopreventive properties, and products containing such constituents are therefore readily consumed. In the present work, we isolated 13 phenolic constituents of four different compound classes from the aerial parts of the Moldavian dragonhead, an aromatic and medicinal plant with a high diversity on secondary metabolites. All compounds were tested for their apoptotic effect on myeloma (KMS-12-PE) and AML (Molm-13) cells, with the highest activity observed for the flavone and flavonol derivatives. While diosmetin (

Indexed as

FlavonesLamiaceaeLeukemia, Myeloid, AcuteLignansMultiple MyelomaCaffeic AcidsCell Line, TumorFlavonolsPhenolscaffeic acidCaffeic AcidsFlavonesFlavonolsLignansPhenolsapigeninapoptosiscytotoxicityFLT3 inhibitorhematologic cancerkaempferolluteolinnatural productquercetinstructure-activity relationship

Identifiers

PMID36430695
PMCPMC9696366
OpenAlexW4309461993

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.