Evidence map›Paper›PMID 36430680›Full record

ReviewInternational journal of molecular sciences2022

Modifier Factors of Cystic Fibrosis Phenotypes: A Focus on Modifier Genes.

Julie Mésinèle, Manon Ruffin, Loïc Guillot, Harriet Corvol

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Role of theInternational journal of molecular sciences · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Cystic Fibrosis: A Journey through Time and Hope.International journal of molecular sciences · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Julie MésinèleSorbonne Université, Inserm U938, Centre de Recherche Saint-Antoine (CRSA), 75012 Paris, France.ORCID 0000-0002-4129-4362
Manon RuffinSorbonne Université, Inserm U938, Centre de Recherche Saint-Antoine (CRSA), 75012 Paris, France.
Loïc GuillotSorbonne Université, Inserm U938, Centre de Recherche Saint-Antoine (CRSA), 75012 Paris, France.ORCID 0000-0001-6853-7945
Harriet CorvolSorbonne Université, Inserm U938, Centre de Recherche Saint-Antoine (CRSA), 75012 Paris, France.ORCID 0000-0002-7026-7523
Inserm · FR

Funding

Fondation pour la Recherche Médicale PMJ201810007620
6 · The paper itself

Abstract

Although cystic fibrosis (CF) is recognized as a monogenic disease, due to variants within the

Indexed as

Cystic FibrosisGenes, ModifierCystic Fibrosis Transmembrane Conductance RegulatorHumansPhenotypeCystic Fibrosis Transmembrane Conductance RegulatorCFTR (Cystic Fibrosis Transmembrane Regulator) modulator therapycystic fibrosisenvironmental factorsmodifiers genes

Identifiers

PMID36430680
PMCPMC9698440
OpenAlexW4309171739

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.