Evidence map›Paper›PMID 36430653›Full record

ArticleInternational journal of molecular sciences2022

A Combination of Rosa Multiflora and Zizyphus Jujuba Enhance Sleep Quality in Anesthesia-Induced Mice.

Sanung Eom, Shinhui Lee, Jiwon Lee, Sung-Oh Sohn, Junho H Lee, Jaeman Park

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Combined Effects ofFoods (Basel, Switzerland) · 2023
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sanung EomDepartment of Biotechnology, Chonnam National University, Gwangju 61186, Republic of Korea.
Shinhui LeeDepartment of Biotechnology, Chonnam National University, Gwangju 61186, Republic of Korea.ORCID 0000-0002-5537-8241
Jiwon LeeDepartment of Biotechnology, Chonnam National University, Gwangju 61186, Republic of Korea.
Sung-Oh SohnR&D Center, Nature Pure Korea, Damyang 57309, Republic of Korea.ORCID 0000-0002-0605-6270
Junho H LeeDepartment of Biotechnology, Chonnam National University, Gwangju 61186, Republic of Korea.ORCID 0000-0003-0913-8578
Jaeman ParkGilbut Korean Medicine Clinic, Seongnam 13144, Republic of Korea.
Chonnam National University · KRDunsan Korean Medicine Hospital · KR

Funding

National Committee for the Development of Technologies S3078597
6 · The paper itself

Abstract

Sleep is an essential component of quality of life. The majority of people experience sleep problems that impact their quality of life. Melatonin is currently a representative sleep aid. However, it is classified as a prescription drug in most countries, and consumers cannot purchase it to improve their sleep. This sleep induction experiment in mice aimed to identify a natural combination product (NCP) that can create synergistic sleep-promoting effects. Based on the mechanism of action of sleep, we investigated whether phenomenological indicators of sleep quality change according to the intake of NCP. The sleep onset and sleep time of the mice that consumed the NCP found by this study were improved compared to the existing sleep aids. The mean melatonin level in the blood increased by 197% compared to the control. To our knowledge, this is the first study to demonstrate that

Indexed as

AnesthesiaMelatoninRosaZiziphusAnimalsMiceQuality of LifeSleep QualityMelatoninbiological clockmelatonin receptorNCP—Rosa multiflora Thunb. (Yeongsil)/Zizyphus jujuba Miller (Sanjoin) natural combination productRosa multiflora Thunb. (Yeongsil)SCN—suprachiasmatic nucleussleepTraditional Korean Medicine

Identifiers

PMID36430653
PMCPMC9696267
OpenAlexW4309605418

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.