Evidence map›Paper›PMID 36430640›Full record

ArticleInternational journal of molecular sciences2022

FSH Regulates YAP-TEAD Transcriptional Activity in Bovine Granulosa Cells to Allow the Future Dominant Follicle to Exert Its Augmented Estrogenic Capacity.

Leonardo Guedes de Andrade, Valério Marques Portela, Esdras Corrêa Dos Santos, Karine de Vargas Aires, Rogério Ferreira, Daniele Missio, Zigomar da Silva, Júlia Koch, Alfredo Quites Antoniazzi, Paulo Bayard Dias Gonçalves and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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  6. Review
  7. Current Insights in Prolactin Signaling and Ovulatory Function.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Leonardo Guedes de AndradeCentre de Recherche en Reproduction et Fertilité, Faculté de Médecine Vétérinaire, Université de Montréal, Saint-Hyacinthe, QC J2S 7C6, Canada.
Valério Marques PortelaLaboratory of Biotechnology and Animal Reproduction (BioRep), Veterinary Hospital, Federal University of Santa Maria (UFSM), Santa Maria 97105-900, Brazil.ORCID 0000-0003-2109-1346
Esdras Corrêa Dos SantosCentre de Recherche en Reproduction et Fertilité, Faculté de Médecine Vétérinaire, Université de Montréal, Saint-Hyacinthe, QC J2S 7C6, Canada.
Karine de Vargas AiresLaboratory of Biotechnology and Animal Reproduction (BioRep), Veterinary Hospital, Federal University of Santa Maria (UFSM), Santa Maria 97105-900, Brazil.ORCID 0000-0002-5662-7529
Rogério FerreiraDepartment of Animal Science, Santa Catarina State University (UDESC), Chapecó 88035-901, Brazil.ORCID 0000-0003-1349-7821
Daniele MissioLaboratory of Biotechnology and Animal Reproduction (BioRep), Veterinary Hospital, Federal University of Santa Maria (UFSM), Santa Maria 97105-900, Brazil.
Zigomar da SilvaLaboratory of Biotechnology and Animal Reproduction (BioRep), Veterinary Hospital, Federal University of Santa Maria (UFSM), Santa Maria 97105-900, Brazil.ORCID 0000-0002-4356-8910
Júlia KochLaboratory of Biotechnology and Animal Reproduction (BioRep), Veterinary Hospital, Federal University of Santa Maria (UFSM), Santa Maria 97105-900, Brazil.
Alfredo Quites AntoniazziLaboratory of Biotechnology and Animal Reproduction (BioRep), Veterinary Hospital, Federal University of Santa Maria (UFSM), Santa Maria 97105-900, Brazil.ORCID 0000-0003-4866-5944
Paulo Bayard Dias GonçalvesLaboratory of Biotechnology and Animal Reproduction (BioRep), Veterinary Hospital, Federal University of Santa Maria (UFSM), Santa Maria 97105-900, Brazil.
Gustavo ZamberlamCentre de Recherche en Reproduction et Fertilité, Faculté de Médecine Vétérinaire, Université de Montréal, Saint-Hyacinthe, QC J2S 7C6, Canada.ORCID 0000-0002-0089-9955
Universidade Federal de Santa Maria · BRUniversité de Montréal · CAUniversidade do Estado de Santa Catarina · BR

Funding

Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul Grant 19/2551-0002275-1Natural Sciences and Engineering Research Council Discovery Grant RGPIN-2018-06470
6 · The paper itself

Abstract

The molecular mechanisms that drive the granulosa cells' (GC) differentiation into a more estrogenic phenotype during follicular divergence and establishment of follicle dominance have not been completely elucidated. The main Hippo signaling effector, YAP, has, however, emerged as a potential key player to explain such complex processes. Studies using rat and bovine GC demonstrate that, in conditions where the expression of the classic YAP-TEAD target gene tissue growth factor (

Indexed as

Follicle Stimulating HormoneOvarian FollicleAnimalsCattleEstroneFemaleGranulosa CellsRatsRNA, MessengerTEA Domain Transcription FactorsVerteporfinYAP-Signaling ProteinsEstroneFollicle Stimulating HormoneRNA, MessengerTEA Domain Transcription FactorsVerteporfinYAP-Signaling ProteinsANKRD1cowCTGFCYR61follicle deviation or divergenceHippoovarysteroidogenesisyes-associated protein 1

Identifiers

PMID36430640
PMCPMC9693326
OpenAlexW4309173106

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.