Evidence map›Paper›PMID 36430572›Full record

ArticleInternational journal of molecular sciences2022

Peripheral Ion Channel Genes Screening in Painful Small Fiber Neuropathy.

Milena Ślęczkowska, Rowida Almomani, Margherita Marchi, Erika Salvi, Bianca T A de Greef, Maurice Sopacua, Janneke G J Hoeijmakers, Patrick Lindsey, Stephen G Waxman, Giuseppe Lauria and 3 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
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  9. Article
  10. Review
  11. TRPV3 Ion Channel: From Gene to Pharmacology.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 4 countries.

Milena ŚlęczkowskaDepartment of Toxicogenomics, Maastricht University, 6229 ER Maastricht, The Netherlands.ORCID 0000-0002-7419-523X
Rowida AlmomaniDepartment of Neurology, School of Mental Health and Neuroscience, Maastricht University Medical Centre+, 6229 ER Maastricht, The Netherlands.
Margherita MarchiNeuroalgology Unit, IRCCS Foundation "Carlo Besta" Neurological Institute, 20133 Milan, Italy.ORCID 0000-0002-5098-8534
Erika SalviNeuroalgology Unit, IRCCS Foundation "Carlo Besta" Neurological Institute, 20133 Milan, Italy.ORCID 0000-0002-2724-2291
Bianca T A de GreefDepartment of Neurology, School of Mental Health and Neuroscience, Maastricht University Medical Centre+, 6229 ER Maastricht, The Netherlands.
Maurice SopacuaDepartment of Neurology, School of Mental Health and Neuroscience, Maastricht University Medical Centre+, 6229 ER Maastricht, The Netherlands.ORCID 0000-0001-8132-1532
Janneke G J HoeijmakersDepartment of Neurology, School of Mental Health and Neuroscience, Maastricht University Medical Centre+, 6229 ER Maastricht, The Netherlands.ORCID 0000-0001-6940-0027
Patrick LindseyDepartment of Toxicogenomics, Maastricht University, 6229 ER Maastricht, The Netherlands.
Stephen G WaxmanDepartment of Neurology, Yale University School of Medicine, New Haven, CT 06510, USA.ORCID 0000-0001-5718-7177
Giuseppe LauriaNeuroalgology Unit, IRCCS Foundation "Carlo Besta" Neurological Institute, 20133 Milan, Italy.
Catharina G FaberDepartment of Neurology, School of Mental Health and Neuroscience, Maastricht University Medical Centre+, 6229 ER Maastricht, The Netherlands.ORCID 0000-0002-2467-067X
Hubert J M SmeetsDepartment of Toxicogenomics, Maastricht University, 6229 ER Maastricht, The Netherlands.
Monique M GerritsDepartment of Clinical Genetics, Maastricht University Medical Centre+, 6229 HX Maastricht, The Netherlands.ORCID 0000-0002-9503-9404
Maastricht University Medical Centre · NLFondazione IRCCS Istituto Neurologico Carlo Besta · ITJordan University of Science and Technology · JOMaastricht University · NLYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
European Union 602273European Union 721841NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

Neuropathic pain is a characteristic feature of small fiber neuropathy (SFN), which in 18% of the cases is caused by genetic variants in voltage-gated sodium ion channels. In this study, we assessed the role of fifteen other ion channels in neuropathic pain. Patients with SFN (n = 414) were analyzed for

Indexed as

Ion ChannelsNeuralgiaSmall Fiber NeuropathyAnoctaminsCohort StudiesDiabetic NeuropathiesHumansPotassium ChannelsANO3 protein, humanAnoctaminsIon ChannelsKCNK18 protein, humanPotassium Channelsidiopathic small fiber neuropathyion channelMIPs-NGSneuropathic painperipheral neuropathy

Identifiers

PMID36430572
PMCPMC9696564
OpenAlexW4309153102

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.