ReviewInternational journal of molecular sciences2022
Sources, Selection, and Microenvironmental Preconditioning of Cells for Urethral Tissue Engineering.
Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 15 citations in OpenAlex.
- When will bioprinting become a therapy? Translational and regulatory challenges in urogenital tissue engineering and surgery.Frontiers in bioengineering and biotechnology · 2026Article
- Current Progress of Tissue Engineering With Stem Cells in Urology Updated Review in 2025.International journal of urology : official journal of the Japanese Urological Association · 2025Review
- Description of the Human Penile Urethra Epithelium.Medicina (Kaunas, Lithuania) · 2025Article
- Experimental study on tissue-engineered urethral graft for repairing urethral defects in a rabbit model.Frontiers in bioengineering and biotechnology · 2025Article
- A double-layer PLGA/CoI-MeHA tissue engineering scaffold for urethral reconstruction.Frontiers in pharmacology · 2025Article
- The effect of platelet-rich fibrin on the biological properties of urothelial cells.Scientific reports · 2024Article
- Optimization of Polycaprolactone and Type I Collagen Scaffold for Tendon Tissue Regeneration.Cureus · 2024Article
- Tissue Engineering for Penile Reconstruction.Bioengineering (Basel, Switzerland) · 2024Review
- Adipose stem cells in tissue regeneration and repair: From bench to bedside.Regenerative therapy · 2023Review
- Cell-Based Therapy for Urethral Regeneration: A Narrative Review and Future Perspectives.Biomedicines · 2023Review
- Biological Macromolecule-Based Scaffolds for Urethra Reconstruction.Biomolecules · 2023Review
- Nanotechnology Involved in Treating Urinary Tract Infections: An Overview.Nanomaterials (Basel, Switzerland) · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Urethral stricture is a common urinary tract disorder in men that can be caused by iatrogenic causes, trauma, inflammation, or infection and often requires reconstructive surgery. The current therapeutic approach for complex urethral strictures usually involves reconstruction with autologous tissue from the oral mucosa. With the goal of overcoming the lack of sufficient autologous tissue and donor site morbidity, research over the past two decades has focused on cell-based tissue-engineered substitutes. While the main focus has been on autologous cells from the penile tissue, bladder, and oral cavity, stem cells from sources such as adipose tissue and urine are competing candidates for future urethral regeneration due to their ease of collection, high proliferative capacity, maturation potential, and paracrine function. This review addresses the sources, advantages, and limitations of cells for tissue engineering in the urethra and discusses recent approaches to improve cell survival, growth, and differentiation by mimicking the mechanical and biophysical properties of the extracellular environment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.