Evidence map›Paper›PMID 36430546›Full record

ArticleInternational journal of molecular sciences2022

Extensive Collection of Psychotropic Mushrooms with Determination of Their Tryptamine Alkaloids.

Klára Gotvaldová, Jan Borovička, Kateřina Hájková, Petra Cihlářová, Alan Rockefeller, Martin Kuchař

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Surprising Variability in Tryptamine Profiles ofJournal of fungi (Basel, Switzerland) · 2026
    Article
  5. Review
  6. Systematic study ofIMA fungus · 2026
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. ExploringJournal of fungi (Basel, Switzerland) · 2025
    Review
  13. Article
  14. Article
  15. Article
  16. Cultivation, chemistry, and genome ofJournal of psychedelic studies · 2024
    Article
  17. Methyl transfer in psilocybin biosynthesis.Nature communications · 2024
    Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Klára GotvaldováForensic Laboratory of Biologically Active Substances, Department of Chemistry of Natural Compounds, University of Chemistry and Technology Prague, Technická 5, 166 28 Praha 6-Dejvice, 166 28 Prague, Czech Republic.ORCID 0000-0002-0774-4454
Jan BorovičkaNuclear Physics Institute of the Czech Academy of Sciences, Hlavní 130, 250 68 Husinec-Řež, Czech Republic.ORCID 0000-0003-3966-558X
Kateřina HájkováForensic Laboratory of Biologically Active Substances, Department of Chemistry of Natural Compounds, University of Chemistry and Technology Prague, Technická 5, 166 28 Praha 6-Dejvice, 166 28 Prague, Czech Republic.
Petra CihlářováForensic Laboratory of Biologically Active Substances, Department of Chemistry of Natural Compounds, University of Chemistry and Technology Prague, Technická 5, 166 28 Praha 6-Dejvice, 166 28 Prague, Czech Republic.ORCID 0000-0001-6552-0697
Alan RockefellerMimosa Therapeutics, 1940 Union St., Oakland, CA 94607, USA.
Martin KuchařForensic Laboratory of Biologically Active Substances, Department of Chemistry of Natural Compounds, University of Chemistry and Technology Prague, Technická 5, 166 28 Praha 6-Dejvice, 166 28 Prague, Czech Republic.ORCID 0000-0002-7616-6352
National Institute of Mental Health · CZCzech Academy of Sciences · CZMimosa Acoustics (United States) · US

Funding

Czech Academy of Sciences RVO67985831Ministry of Health NU21-04-00307
6 · The paper itself

Abstract

Since not only psilocybin (PSB) but also PSB-containing mushrooms are used for psychedelic therapy and microdosing, it is necessary to know their concentration variability in wild-grown mushrooms. This article aimed to determine the PSB, psilocin (PS), baeocystin (BA), norbaeocystin (NB), and aeruginascin (AE) concentrations in a large sample set of mushrooms belonging to genera previously reported to contain psychotropic tryptamines. Ultra-high performance liquid chromatography coupled with tandem mass spectrometry was used to quantify tryptamine alkaloids in the mushroom samples. Most mushroom collections were documented by fungarium specimens and/or ITS rDNA/LSU/EF1-α sequencing. Concentrations of five tryptamine alkaloids were determined in a large sample set of 226 fruiting bodies of 82 individual collections from seven mushroom genera. For many mushroom species, concentrations of BA, NB, and AE are reported for the first time. The highest PSB/PS concentrations were found in

Indexed as

AgaricalesAlkaloidsIndolesOrganophosphatesOrganophosphorus CompoundsTryptaminesAlkaloidsbaeocystinIndolesN, N, N-trimethyl-4-phosphoryloxytryptamineOrganophosphatesOrganophosphorus CompoundstryptamineTryptaminesbaeocystinhallucinogenic fungipsilocinPsilocybepsilocybin

Identifiers

PMID36430546
PMCPMC9693126
OpenAlexW4309210963

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.