Evidence map›Paper›PMID 36430525›Full record

ArticleInternational journal of molecular sciences2022

Peptides for Coating TiO

Almerinda Agrelli, Niedja Fittipaldi Vasconcelos, Rayane Cristine Santos da Silva, Carina Lucena Mendes-Marques, Isabel Renata de Souza Arruda, Priscilla Stela Santana de Oliveira, Luzia Rejane Lisbôa Santos, Audrey Nunes de Andrade, Ronald Rodrigues de Moura, Lucas Coelho Bernardo-Menezes and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. KRSR and RGD Adsorption on TiOBiomolecules · 2026
    Article
  2. Osseointegration Process ImprovingCurrent topics in medicinal chemistry · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Almerinda AgrelliLaboratory of Nanostructured Materials (LMNANO), Strategic Technologies Center of Northeast (CETENE), Recife 50740-545, Brazil.ORCID 0000-0002-9908-742X
Niedja Fittipaldi VasconcelosLaboratory of Nanostructured Materials (LMNANO), Strategic Technologies Center of Northeast (CETENE), Recife 50740-545, Brazil.
Rayane Cristine Santos da SilvaLaboratory of Nanostructured Materials (LMNANO), Strategic Technologies Center of Northeast (CETENE), Recife 50740-545, Brazil.
Carina Lucena Mendes-MarquesLaboratory of Nanostructured Materials (LMNANO), Strategic Technologies Center of Northeast (CETENE), Recife 50740-545, Brazil.ORCID 0000-0002-3111-7063
Isabel Renata de Souza ArrudaLaboratory of Nanostructured Materials (LMNANO), Strategic Technologies Center of Northeast (CETENE), Recife 50740-545, Brazil.
Priscilla Stela Santana de OliveiraLaboratory of Nanostructured Materials (LMNANO), Strategic Technologies Center of Northeast (CETENE), Recife 50740-545, Brazil.
Luzia Rejane Lisbôa SantosLaboratory of Nanostructured Materials (LMNANO), Strategic Technologies Center of Northeast (CETENE), Recife 50740-545, Brazil.ORCID 0000-0002-2435-3957
Audrey Nunes de AndradeLaboratory of Nanostructured Materials (LMNANO), Strategic Technologies Center of Northeast (CETENE), Recife 50740-545, Brazil.ORCID 0000-0003-2671-6069
Ronald Rodrigues de MouraDepartment of Advanced Diagnostics, IRCCS Materno Infantile Burlo Garofolo, 34137 Trieste, Italy.ORCID 0000-0002-9112-7167
Lucas Coelho Bernardo-MenezesLaboratory of Virology and Experimental Therapeutics (LaViTE), Aggeu Magalhães Institute, Oswaldo Cruz Foundation (FIOCRUZ), Recife 50670-420, Brazil.ORCID 0000-0003-4523-4276
Natália Pereira da SilvaNortheast Biotechnology Network (RENORBIO), Postgraduation Program in Biotechnology, Federal University of Pernambuco, Recife 50670-901, Brazil.ORCID 0000-0003-4575-5143
Giovanna MachadoLaboratory of Nanostructured Materials (LMNANO), Strategic Technologies Center of Northeast (CETENE), Recife 50740-545, Brazil.ORCID 0000-0002-9058-3056
Centro de Tecnologias Estratégicas do Nordeste · BRFundação Oswaldo Cruz · BRIRCCS Materno Infantile Burlo Garofolo · ITUniversidade Federal de Pernambuco · BR

Funding

Financiadora de Estudos e Projetos - FINEP Materiais Avançados 29401Fundação de Amparo à Ciência e Tecnologia de Pernambuco APQ-0516-9.25/19National Council for Scientific and Technological Development 442477/2019-8the Institute for Maternal and Child Health IRCCS "Burlo Garofolo/Italian Ministry of Health BioHub 03/20
6 · The paper itself

Abstract

Titanium is usually used in the manufacturing of metal implants due to its biocompatibility and high resistance to corrosion. A structural and functional connection between the living bone and the surface of the implant, a process called osseointegration, is mandatory for avoiding prolonged healing, infections, and tissue loss. Therefore, osseointegration is crucial for the success of the implantation procedure. Osseointegration is a process mediated by bone-matrix progenitor cells' proteins, named integrins. In this study, we used an in silico approach to assemble and test peptides that can be strategically used in sensitizing TiO

Indexed as

Coated Materials, BiocompatibleTitaniumIntegrinsPeptidesCoated Materials, BiocompatibleIntegrinsPeptidesTitaniumtitanium dioxidemolecular dockingmolecular dynamicsosseointegrationTiO2 implantstitanium

Identifiers

PMID36430525
PMCPMC9693858
OpenAlexW4309026080

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.