Evidence map›Paper›PMID 36430509›Full record

ArticleInternational journal of molecular sciences2022

Methyl Gallate Alleviates Acute Ulcerative Colitis by Modulating Gut Microbiota and Inhibiting TLR4/NF-κB Pathway.

Ping Zhou, Jia Lai, Yueyue Li, Junzhu Deng, Chunling Zhao, Qianqian Huang, Fei Yang, Shuo Yang, Yuesong Wu, Xiaoqin Tang and 5 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. [Methyl syringate alleviates DSS-induced colitis in mice by suppressing intestinal epithelial cell apoptosisNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2026
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  13. Pharmaceuticals (Basel, Switzerland) · 2023
    Article
  14. Article
  15. Ethyl acetate extract ofFrontiers in pharmacology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Ping ZhouSchool of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Jia LaiSchool of Pharmacy, Southwest Medical University, Luzhou 646000, China.
Yueyue LiSchool of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Junzhu DengSchool of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Chunling ZhaoSchool of Basic Medical Sciences, Southwest Medical University, Luzhou 646000, China.
Qianqian HuangLuzhou Key Laboratory of Activity Screening and Druggability Evaluation for Chinese Materia Medica, Southwest Medical University, Luzhou 646000, China.
Fei YangSchool of Pharmacy, Southwest Medical University, Luzhou 646000, China.
Shuo YangSchool of Pharmacy, Southwest Medical University, Luzhou 646000, China.
Yuesong WuSchool of Pharmacy, Southwest Medical University, Luzhou 646000, China.
Xiaoqin TangSchool of Pharmacy, Southwest Medical University, Luzhou 646000, China.
Feihong HuangSchool of Pharmacy, Southwest Medical University, Luzhou 646000, China.
Long WangSchool of Pharmacy, Southwest Medical University, Luzhou 646000, China.
Xinwu HuangSchool of Pharmacy, Southwest Medical University, Luzhou 646000, China.
Wenjun ZouSchool of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Jianming WuSchool of Basic Medical Sciences, Southwest Medical University, Luzhou 646000, China.ORCID 0000-0002-6136-7469
Southwest Medical University · CNChengdu University of Traditional Chinese Medicine · CN

Funding

National Natural Science Foundation of China 82074129, 81804221 and 82204666
6 · The paper itself

Abstract

Ulcerative colitis (UC) is a complex immune-mediated inflammatory disease. In recent years, the incidence of UC has increased rapidly, however, its exact etiology and mechanism are still unclear. Based on the definite anti-inflammatory and antibacterial activities of

Indexed as

Colitis, UlcerativeGastrointestinal MicrobiomeAnimalsGallic AcidMiceNF-kappa BRNA, Ribosomal, 16SToll-Like Receptor 4Gallic Acidmethyl gallateNF-kappa BRNA, Ribosomal, 16STlr4 protein, mouseToll-Like Receptor 4gut immunitygut microbiotamethyl gallateTLR4/NF-κBulcerative colitis

Identifiers

PMID36430509
PMCPMC9697899
OpenAlexW4309026864

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.