Evidence map›Paper›PMID 36430484›Full record

ArticleInternational journal of molecular sciences2022

Preparation of Nano/Microcapsules of Ozonated Olive Oil in Hyaluronan Matrix and Analysis of Physicochemical and Microbiological (Biological) Properties of the Obtained Biocomposite.

Gohar Khachatryan, Lusine Khachatryan, Magdalena Krystyjan, Anna Lenart-Boroń, Marcel Krzan, Klaudia Kulik, Anna Białecka, Maja Grabacka, Nikola Nowak, Karen Khachatryan

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Gohar KhachatryanFaculty of Food Technology, University of Agriculture in Krakow, Mickiewicz Ave. 21, 31-120 Krakow, Poland.ORCID 0000-0002-4601-7145
Lusine KhachatryanDepartment of Orthopaedics and Traumatology, University Hospital in Cracow, Macieja Jakubowskiego 2, 30-688 Krakow, Poland.
Magdalena KrystyjanFaculty of Food Technology, University of Agriculture in Krakow, Mickiewicz Ave. 21, 31-120 Krakow, Poland.ORCID 0000-0001-9490-0939
Anna Lenart-BorońDepartment of Microbiology and Biomonitoring, Faculty of Agriculture and Economics, University of Agriculture in Krakow, 30-059 Krakow, Poland.ORCID 0000-0003-3655-7567
Marcel KrzanJerzy Haber Institute of Catalysis and Surface Chemistry, Polish Academy of Sciences, Niezapominajek 8, 30-239 Krakow, Poland.ORCID 0000-0002-7469-3247
Klaudia KulikDepartment of Microbiology and Biomonitoring, Faculty of Agriculture and Economics, University of Agriculture in Krakow, 30-059 Krakow, Poland.ORCID 0000-0001-6392-1454
Anna BiałeckaJan Bober Center for Microbiology and Autovaccines, 31-016 Krakow, Poland.
Maja GrabackaFaculty of Food Technology, University of Agriculture in Krakow, Mickiewicz Ave. 21, 31-120 Krakow, Poland.ORCID 0000-0003-4407-8814
Nikola NowakFaculty of Food Technology, University of Agriculture in Krakow, Mickiewicz Ave. 21, 31-120 Krakow, Poland.ORCID 0000-0001-5897-9520
Karen KhachatryanFaculty of Food Technology, University of Agriculture in Krakow, Mickiewicz Ave. 21, 31-120 Krakow, Poland.ORCID 0000-0001-7823-5406
University of Agriculture in Krakow · PLJerzy Haber Institute of Catalysis and Surface Chemistry, Polish Academy of Sciences · PLŁukasiewicz Research Network · PL

Funding

European Regional Development Fund - Smart Growth Operational Programme SA 42799 (2015/X)Ministry of Science and Higher Education subsidy for the University of Agriculture in Krakow for 2022; subsidy for Jerzy Haber Institute of Catalysis and Surface Chemistry PAS
6 · The paper itself

Abstract

Hydrogels, based on natural polymers, such as hyaluronic acid, are gaining an increasing popularity because of their biological activity. The antibacterial effect of ozone is widely known and used, but the instability the gas causes, severely limits its application. Ozone entrapment in olive oil by its reaction with an unsaturated bond, allows for the formation of stable, therapeutically active ozone derivatives. In this study, we obtained an innovative hydrogel, based on hyaluronic acid containing micro/nanocapsules of ozonated olive oil. By combination of the biocompatible polymer with a high regenerative capacity and biologically active ingredients, we obtained a hydrogel with regenerative properties and a very weak inhibitory effect against both bacterial commensal skin microbiota and pathogenic

Indexed as

Anti-Infective AgentsOzoneAnti-Bacterial AgentsCapsulesHumansHyaluronic AcidHydrogelsOlive OilPolymersAnti-Bacterial AgentsAnti-Infective AgentsCapsulesHyaluronic AcidHydrogelsOlive OilOzonePolymershyaluronic acidin vitronanocapsulesolive oilozonerheology

Identifiers

PMID36430484
PMCPMC9694719
OpenAlexW4308973093

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.