Evidence map›Paper›PMID 36430456›Full record

ArticleInternational journal of molecular sciences2022

Chromosomally Unstable Gastric Cancers Overexpressing Claudin-6 Disclose Cross-Talk between HNF1A and HNF4A, and Upregulated Cholesterol Metabolism.

Sanyog Dwivedi, Georgina Hernández-Montes, Luis Felipe Montaño, Erika Patricia Rendón-Huerta

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sanyog DwivediLaboratorio de Inmunobiología, Departamento de Biología Celular y Tisular, Facultad de Medicina, UNAM, Ciudad de México 04510, Mexico.
Georgina Hernández-MontesRed de Apoyo a la Investigación, Instituto Nacional de Ciencias Médicas y Nutrición "Dr. Salvador Zubiran", Ciudad de México 14080, Mexico.
Luis Felipe MontañoLaboratorio de Inmunobiología, Departamento de Biología Celular y Tisular, Facultad de Medicina, UNAM, Ciudad de México 04510, Mexico.
Erika Patricia Rendón-HuertaLaboratorio de Inmunobiología, Departamento de Biología Celular y Tisular, Facultad de Medicina, UNAM, Ciudad de México 04510, Mexico.
Universidad Nacional Autónoma de México · MXInstituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán · MX

Funding

National Autonomous University of Mexico IN218019
6 · The paper itself

Abstract

(1) Abnormally increased expression of claudin-6 in gastric cancer is considered a prognostic marker of the chromosomal unstable molecular subtype. However, a detailed molecular profile analysis of differentially expressed genes and affected pathways associated with claudin-6 increased (Cldn6

Indexed as

AdenocarcinomaStomach NeoplasmsApolipoprotein C-IIICholesterolClaudinsHepatocyte Nuclear Factor 1-alphaHepatocyte Nuclear Factor 4HumansIntracellular Signaling Peptides and ProteinsNeoplasm ProteinsApolipoprotein C-IIICholesterolclaudin 6ClaudinsHepatocyte Nuclear Factor 1-alphaHepatocyte Nuclear Factor 4HNF1A protein, humanHNF4A protein, humanIntracellular Signaling Peptides and ProteinsMIEN1 protein, humanNeoplasm Proteinscholesterol metabolismclaudin-6gastric cancer

Identifiers

PMID36430456
PMCPMC9694805
OpenAlexW4309008089

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.