Evidence map›Paper›PMID 36430396›Full record

ArticleInternational journal of molecular sciences2022

In Vitro and In Vivo Response of Zinc-Containing Mesoporous Bioactive Glasses in a Sheep Animal Model.

Javier Jiménez-Holguín, Daniel Arcos, Daniel Lozano, Melchor Saiz-Pardo, David de Pablo, Luis Ortega, Silvia Enciso, Blanca Fernández-Tomé, Idoia Díaz-Güemes, Francisco Miguel Sánchez-Margallo and 3 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Nanomaterials in Biomedicine 2022.International journal of molecular sciences · 2023
    Article
  4. Mesoporous Bioactive Nanoparticles for Bone Tissue Applications.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Javier Jiménez-HolguínDepartamento de Química en Ciencias Farmacéuticas, Facultad de Farmacia, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Hospital 12 de Octubre i+12, Plaza Ramón y Cajal s/n, 28040 Madrid, Spain.ORCID 0000-0002-0317-4984
Daniel ArcosDepartamento de Química en Ciencias Farmacéuticas, Facultad de Farmacia, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Hospital 12 de Octubre i+12, Plaza Ramón y Cajal s/n, 28040 Madrid, Spain.
Daniel LozanoDepartamento de Química en Ciencias Farmacéuticas, Facultad de Farmacia, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Hospital 12 de Octubre i+12, Plaza Ramón y Cajal s/n, 28040 Madrid, Spain.ORCID 0000-0001-5902-9201
Melchor Saiz-PardoServicio de Anatomía Patológica, Hospital Clínico San Carlos, Facultad de Medicina, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.
David de PabloServicio de Anatomía Patológica, Hospital Clínico San Carlos, Facultad de Medicina, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.ORCID 0000-0003-0286-6089
Luis OrtegaServicio de Anatomía Patológica, Hospital Clínico San Carlos, Facultad de Medicina, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.
Silvia EncisoCentro de Cirugía de Mínima Invasión Jesús Usón, NANBIOSIS, 10071 Cáceres, Spain.
Blanca Fernández-ToméCentro de Cirugía de Mínima Invasión Jesús Usón, NANBIOSIS, 10071 Cáceres, Spain.
Idoia Díaz-GüemesCentro de Cirugía de Mínima Invasión Jesús Usón, NANBIOSIS, 10071 Cáceres, Spain.
Francisco Miguel Sánchez-MargalloCentro de Cirugía de Mínima Invasión Jesús Usón, NANBIOSIS, 10071 Cáceres, Spain.ORCID 0000-0003-2138-988X
Laura CasarrubiosDepartamento de Bioquímica y Biología Molecular, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.
María Teresa PortolésCIBER de Bioingeniería, Biomateriales y Nanomedicina, CIBER-BBN, ISCIII, 28040 Madrid, Spain.
María Vallet-RegíDepartamento de Química en Ciencias Farmacéuticas, Facultad de Farmacia, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Hospital 12 de Octubre i+12, Plaza Ramón y Cajal s/n, 28040 Madrid, Spain.ORCID 0000-0002-6104-4889
Universidad Complutense de Madrid · ESCentro de Cirugía de Mínima Invasión Jesús Usón · ES

Funding

European Research Council 694160European Research Council ERC-2015-AdG Proposal No. 694160Ministerio de Ciencia e Innovación MAT2016-75611-RMinisterio de Ciencia e Innovación PID2020-11709RB-I00
6 · The paper itself

Abstract

Zinc-enriched mesoporous bioactive glasses (MBGs) are bioceramics with potential antibacterial and osteogenic properties. However, few assays have been performed to study these properties in animal models. In this study, MBGs enriched with up to 5% ZnO were synthesized, physicochemically characterized, and evaluated for their osteogenic activity both in vitro and in vivo. The ZnO MBGs showed excellent textural properties despite ZnO incorporation. However, the release of Zn

Indexed as

ZincZinc OxideAnimalsGlassModels, AnimalPorositySheepZincZinc Oxidebioactivitybone regenerationcell culturesin vivo studymesoporous bioactive glasszinc

Identifiers

PMID36430396
PMCPMC9698899
OpenAlexW4309009616

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.