Evidence map›Paper›PMID 36430385›Full record

ArticleInternational journal of molecular sciences2022

Development of Radiosterilized Porcine Skin Electrosprayed with Silver Nanoparticles Prevents Infections in Deep Burns.

Mario Alberto Pérez-Díaz, Elizabeth Alvarado-Gómez, María Esther Martínez-Pardo, Miguel José Yacamán, Andrés Flores-Santos, Roberto Sánchez-Sánchez, Fidel Martínez-Gutiérrez, Horacio Bach

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Mario Alberto Pérez-DíazLaboratorio de Biotecnología, Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra (INR-LGII), Calzada México Xochimilco No. 289, Colonia Arenal de Guadalupe, Tlalpan, Ciudad de México 14389, Mexico.
Elizabeth Alvarado-GómezLaboratorio de Antimicrobianos, Biopelículas y Microbiota, Facultad de Ciencias Químicas, Universidad Autónoma de San Luis Potosí, Av. Dr. Manuel Nava No. 6, Zona Universitaria, San Luis Potosí 78210, Mexico.
María Esther Martínez-PardoBanco de Tejidos Radioesterilizados, Instituto Nacional de Investigaciones Nucleares (BTR-ININ), Carretera México-Toluca S/N La Marquesa, Ocoyoacac 52750, Mexico.
Miguel José YacamánApplied Physics and Materials Science Department, Core Faculty Center for Materials Interfaces in Research and Applications (MIRA), Northern Arizona University, Flagstaff, AZ 86011, USA.
Andrés Flores-SantosLaboratorio de Antimicrobianos, Biopelículas y Microbiota, Facultad de Ciencias Químicas, Universidad Autónoma de San Luis Potosí, Av. Dr. Manuel Nava No. 6, Zona Universitaria, San Luis Potosí 78210, Mexico.
Roberto Sánchez-SánchezUnidad de Ingeniería de Tejidos Terapia Celular y Medicina Regenerativa, Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra (INR-LGII), Calzada México Xochimilco No. 289, Colonia Arenal de Guadalupe, Tlalpan, Ciudad de México 14389, Mexico.
Fidel Martínez-GutiérrezLaboratorio de Antimicrobianos, Biopelículas y Microbiota, Facultad de Ciencias Químicas, Universidad Autónoma de San Luis Potosí, Av. Dr. Manuel Nava No. 6, Zona Universitaria, San Luis Potosí 78210, Mexico.
Horacio BachDivision of Infectious Diseases, Department of Medicine, University of British Columbia, 2660 Oak Street, Vancouver, BC V6H 3Z6, Canada.ORCID 0000-0002-7740-9299
Autonomous University of San Luis Potosí · MXInstituto Nacional de Rehabilitación · MXInstituto Nacional de Investigaciones Nucleares · MXNorthern Arizona University · USUniversity of British Columbia · CA

Funding

Consejo Nacional de Ciencia y Tecnología B-S-40505International Atomic Energy Agency Research Contract No. 18278
6 · The paper itself

Abstract

Extensive burns represent a significant challenge in biomedicine due to the multiple systemic and localized complications resulting from the major skin barrier loss. The functionalization of xenografts with nanostructured antibacterial agents proposes a fast and accessible application to restore barrier function and prevent localized bacterial contamination. Based on this, the objective of this work was to functionalize a xenograft by electrospray deposition with silver nanoparticles (AgNPs) and to evaluate its antibiofilm and cytotoxic effects on human fibroblasts. Initially, AgNPs were synthesized by a green microwave route with sizes of 2.1, 6.8, and 12.2 nm and concentrations of 0.055, 0.167, and 0.500 M, respectively. The AgNPs showed a size relationship directly proportional to the concentration of AgNO

Indexed as

BurnsMetal NanoparticlesAnimalsAnti-Bacterial AgentsBacteriaBiofilmsHumansSilverSwineAnti-Bacterial AgentsSilverantibiofilm activityburnscytotoxicityelectrospraymicrowave synthesismultidrug-resistantnanoparticle deposition

Identifiers

PMID36430385
PMCPMC9698029
OpenAlexW4308974855

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.