Evidence map›Paper›PMID 36430295›Full record

ArticleInternational journal of molecular sciences2022

Dynamic Double Cross-Linked Self-Healing Polysaccharide Hydrogel Wound Dressing Based on Schiff Base and Thiol-Alkynone Reactions.

Zhuojun Zhang, Jiasen Bu, Biyun Li, Hongyun Xuan, Yan Jin, Huihua Yuan

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Polysaccharides from South TunisianPlants (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Zhuojun ZhangSchool of Life Sciences, Nantong University, Nantong 226019, China.
Jiasen BuSchool of Life Sciences, Nantong University, Nantong 226019, China.
Biyun LiSchool of Life Sciences, Nantong University, Nantong 226019, China.
Hongyun XuanSchool of Life Sciences, Nantong University, Nantong 226019, China.
Yan JinSchool of Life Sciences, Nantong University, Nantong 226019, China.ORCID 0000-0003-4664-4787
Huihua YuanSchool of Life Sciences, Nantong University, Nantong 226019, China.ORCID 0000-0001-8657-984X
Nantong University · CN

Funding

National Natural Science Foundation of China 32000965 and 81801856
6 · The paper itself

Abstract

In this study, a hydrogel composite wound dressing with antibacterial and self-healing ability was prepared using cysteine-modified carboxymethyl chitosan, sodium oxidized alginate, and but-3-yn-2-one base on Schiff base and thiol-alkynone double cross-links. The structure and properties of the hydrogel were characterized by scanning electron microscope, Fourier-transform infrared, and rheological test, followed by antibacterial and in vivo biocompatibility tests. The results showed that the hydrogel exhibited good self-healing, mechanical properties, good antibacterial effect, and in vivo biocompatibility, and can inhibit inflammation and promote skin tissue regeneration in mice. This novel self-healing hydrogel dressing has a broad application prospect in skin tissue engineering.

Indexed as

DeafnessPrunellaAnimalsAnti-Bacterial AgentsBandagesDietary CarbohydratesHydrogelsMicePolysaccharidesSchiff BasesSulfhydryl CompoundsAnti-Bacterial AgentsDietary CarbohydratesHydrogelsPolysaccharidesSchiff BasesSulfhydryl Compoundsantibacterialdouble cross-linkshydrogelskin repairwound dressing

Identifiers

PMID36430295
PMCPMC9699423
OpenAlexW4308867395

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.