Evidence map›Paper›PMID 36430279›Full record

ArticleInternational journal of molecular sciences2022

Phenethyl Isothiocyanate-Conjugated Chitosan Oligosaccharide Nanophotosensitizers for Photodynamic Treatment of Human Cancer Cells.

Inho Bae, Taeyu Grace Kim, Taeyeon Kim, Dohoon Kim, Doug-Hoon Kim, Jaewon Jo, Young-Ju Lee, Young-Il Jeong

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Chlorin Activity Enhancers for Photodynamic Therapy.Molecules (Basel, Switzerland) · 2025
    Review
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Inho BaeDepartment of Dental Materials, College of Dentistry, Chosun University, Gwangju 61452, Korea.
Taeyu Grace KimTyros Biotechnology Inc., 75 Kneeland St. 14 floors, Boston, MA 02111, USA.
Taeyeon KimCollege of Art & Science, University of Pennsylvania, 249 S 36th St., Philadelphia, PA 19104, USA.
Dohoon KimTyros Biotechnology Inc., 75 Kneeland St. 14 floors, Boston, MA 02111, USA.
Doug-Hoon KimDepartment of Optometry, Masan University, Changwon 51217, Korea.
Jaewon JoGwangju Center, Korea Basic Science Institute, Gwangju 61186, Korea.
Young-Ju LeeGwangju Center, Korea Basic Science Institute, Gwangju 61186, Korea.
Young-Il JeongTyros Biotechnology Inc., 75 Kneeland St. 14 floors, Boston, MA 02111, USA.ORCID 0000-0002-9832-4331
Brookline Public Schools · USKorea Basic Science Institute · KRMasan University · KRChosun University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study is to synthesize phenethyl-conjugated chitosan oligosaccharide (COS) (abbreviated as ChitoPEITC) conjugates and then fabricate chlorin E6 (Ce6)-incorporated nanophotosensitizers for photodynamic therapy (PDT) of HCT-116 colon carcinoma cells. PEITC was conjugated with the amine group of COS. Ce6-incorporated nanophotosensitizers using ChitoPEITC (ChitoPEITC nanophotosensitizers) were fabricated by dialysis method.

Indexed as

CarcinomaChitosanColonic NeoplasmsAnimalsHumansIsothiocyanatesMiceOligosaccharidesReactive Oxygen SpeciesChitosanIsothiocyanatesOligosaccharidesphenethyl isothiocyanateReactive Oxygen Speciesnanophotosensitizersoral cancersphotodynamic therapyreactive oxygen speciestumor-targeting

Identifiers

PMID36430279
PMCPMC9693342
OpenAlexW4308870410

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.