Evidence map›Paper›PMID 36430258›Full record

ArticleInternational journal of molecular sciences2022

Association of LTA and SOD Gene Polymorphisms with Cerebral White Matter Hyperintensities in Migraine Patients.

Patrizia Ferroni, Raffaele Palmirotta, Gabriella Egeo, Cinzia Aurilia, Maria Giovanna Valente, Antonella Spila, Alberto Pierallini, Piero Barbanti, Fiorella Guadagni

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Headache associated with adverse cognitive trajectories in Chinese aging cohort: a group-based trajectory modeling study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
  3. Review
  4. Article
  5. Oxidative Stress and Migraine.Molecular neurobiology · 2024
    Review
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Patrizia FerroniInterinstitutional Multidisciplinary Biobank (BioBIM), IRCCS San Raffaele Roma, 00166 Rome, Italy.ORCID 0000-0002-9877-8712
Raffaele PalmirottaInterdisciplinary Department of Medicine, School of Medicine, University of Bari "Aldo Moro", 70124 Bari, Italy.ORCID 0000-0002-9401-7377
Gabriella EgeoHeadache and Pain Unit, IRCCS San Raffaele Roma, 00163 Rome, Italy.
Cinzia AuriliaHeadache and Pain Unit, IRCCS San Raffaele Roma, 00163 Rome, Italy.ORCID 0000-0002-2658-2243
Maria Giovanna ValenteInterinstitutional Multidisciplinary Biobank (BioBIM), IRCCS San Raffaele Roma, 00166 Rome, Italy.
Antonella SpilaDepartment of Human Sciences and Quality of Life Promotion, San Raffaele Roma Open University, 00166 Rome, Italy.
Alberto PieralliniDepartment of Radiology, IRCCS San Raffaele Roma, 00163 Rome, Italy.
Piero BarbantiDepartment of Human Sciences and Quality of Life Promotion, San Raffaele Roma Open University, 00166 Rome, Italy.
Fiorella GuadagniInterinstitutional Multidisciplinary Biobank (BioBIM), IRCCS San Raffaele Roma, 00166 Rome, Italy.
The Open University · GBIstituti di Ricovero e Cura a Carattere Scientifico · ITIRCCS Ospedale San Raffaele · ITUniversity of Bari Aldo Moro · IT

Funding

Governo Italiano PNR 2015-2020 ARS01_01163 PerMedNet - CUP B66G18000220005Italian Ministry of Health Ricerca Corrente
6 · The paper itself

Abstract

White matter hyperintensities (WMHs) in migraine could be related to inflammatory and antioxidant events. The aim of this study is to verify whether migraine patients with WMHs carry a genetic pro-inflammatory/pro-oxidative status. To test this hypothesis, we analyzed

Indexed as

Migraine DisordersWhite MatterAntioxidantsHumansLymphotoxin-alphaPolymorphism, Single NucleotideSuperoxide DismutaseSuperoxide Dismutase-1AntioxidantsLymphotoxin-alphaSuperoxide DismutaseSuperoxide Dismutase-1genetic variantsinflammationlymphotoxin αmigraineoxidant stresssuperoxide dismutasewhite matter hyperintensities

Identifiers

PMID36430258
PMCPMC9695025
OpenAlexW4308869737

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.