Evidence map›Paper›PMID 36430152›Full record

ArticleInternational journal of molecular sciences2022

circSMARCA5 Is an Upstream Regulator of the Expression of miR-126-3p, miR-515-5p, and Their mRNA Targets,

Aurora Eliana Merulla, Michele Stella, Cristina Barbagallo, Rosalia Battaglia, Angela Caponnetto, Giuseppe Broggi, Roberto Altieri, Francesco Certo, Rosario Caltabiano, Marco Ragusa and 4 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

  1. High-throughput UPCAnalytical and bioanalytical chemistry · 2026
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  3. Review
  4. Review
  5. The Role of RAS in CNS Tumors: A Key Player or an Overlooked Oncogene?International journal of molecular sciences · 2025
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. The Glioblastoma CircularRNAome.International journal of molecular sciences · 2023
    Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Aurora Eliana MerullaDepartment of Biomedical and Biotechnological Sciences, Section of Biology and Genetics "Giovanni Sichel", University of Catania, Via Santa Sofia 89, 95123 Catania, Italy.
Michele StellaDepartment of Biomedical and Biotechnological Sciences, Section of Biology and Genetics "Giovanni Sichel", University of Catania, Via Santa Sofia 89, 95123 Catania, Italy.ORCID 0000-0002-3852-9933
Cristina BarbagalloDepartment of Biomedical and Biotechnological Sciences, Section of Biology and Genetics "Giovanni Sichel", University of Catania, Via Santa Sofia 89, 95123 Catania, Italy.
Rosalia BattagliaDepartment of Biomedical and Biotechnological Sciences, Section of Biology and Genetics "Giovanni Sichel", University of Catania, Via Santa Sofia 89, 95123 Catania, Italy.ORCID 0000-0002-4868-3045
Angela CaponnettoDepartment of Biomedical and Biotechnological Sciences, Section of Biology and Genetics "Giovanni Sichel", University of Catania, Via Santa Sofia 89, 95123 Catania, Italy.
Giuseppe BroggiDepartment of Medical, Surgical Sciences and Advanced Technologies "G.F. Ingrassia", Section of Anatomic Pathology, University of Catania, Via Santa Sofia 87, 95123 Catania, Italy.ORCID 0000-0003-2576-6523
Roberto AltieriInterdisciplinary Research Centre on the Diagnosis and Therapy of Brain Tumors, University of Catania, Via Santa Sofia 78, 95123 Catania, Italy.ORCID 0000-0003-2671-4944
Francesco CertoInterdisciplinary Research Centre on the Diagnosis and Therapy of Brain Tumors, University of Catania, Via Santa Sofia 78, 95123 Catania, Italy.
Rosario CaltabianoDepartment of Medical, Surgical Sciences and Advanced Technologies "G.F. Ingrassia", Section of Anatomic Pathology, University of Catania, Via Santa Sofia 87, 95123 Catania, Italy.ORCID 0000-0001-8591-8010
Marco RagusaDepartment of Biomedical and Biotechnological Sciences, Section of Biology and Genetics "Giovanni Sichel", University of Catania, Via Santa Sofia 89, 95123 Catania, Italy.ORCID 0000-0002-4282-920X
Giuseppe Maria Vincenzo BarbagalloInterdisciplinary Research Centre on the Diagnosis and Therapy of Brain Tumors, University of Catania, Via Santa Sofia 78, 95123 Catania, Italy.
Cinzia Di PietroDepartment of Biomedical and Biotechnological Sciences, Section of Biology and Genetics "Giovanni Sichel", University of Catania, Via Santa Sofia 89, 95123 Catania, Italy.ORCID 0000-0002-6036-4469
Michele PurrelloDepartment of Biomedical and Biotechnological Sciences, Section of Biology and Genetics "Giovanni Sichel", University of Catania, Via Santa Sofia 89, 95123 Catania, Italy.ORCID 0000-0001-8873-3660
Davide BarbagalloDepartment of Biomedical and Biotechnological Sciences, Section of Biology and Genetics "Giovanni Sichel", University of Catania, Via Santa Sofia 89, 95123 Catania, Italy.ORCID 0000-0001-5331-4554
University of Catania · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The involvement of non-coding RNAs (ncRNAs) in glioblastoma multiforme (GBM) pathogenesis and progression has been ascertained but their cross-talk within GBM cells remains elusive. We previously demonstrated the role of circSMARCA5 as a tumor suppressor (TS) in GBM. In this paper, we explore the involvement of circSMARCA5 in the control of microRNA (miRNA) expression in GBM. By using TaqMan

Indexed as

GlioblastomaMicroRNAsGene Expression Regulation, NeoplasticGTP PhosphohydrolasesHumansInsulin-Like Growth Factor Binding Protein 2Membrane ProteinsProto-OncogenesRNA, MessengerGTP PhosphohydrolasesInsulin-Like Growth Factor Binding Protein 2Membrane ProteinsMicroRNAsMIRN126 microRNA, humanMIRN515 microRNA, humanNRAS protein, humanRNA, MessengercircSMARCA5circular RNAepigeneticsmicroRNAomemicroRNA processingmicroRNA targetRNA binding proteintumor suppressor

Identifiers

PMID36430152
PMCPMC9690846
OpenAlexW4308568251

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.