Evidence map›Paper›PMID 36429988›Full record

ArticleInternational journal of environmental research and public health2022

Assessment of Health-Related Quality of Life, Medication Adherence, and Prevalence of Depression in Kidney Failure Patients.

Muhammad Daoud Butt, Siew Chin Ong, Fatima Zahid Butt, Ahsan Sajjad, Muhammad Fawad Rasool, Imran Imran, Tanveer Ahmad, Faleh Alqahtani, Zaheer-Ud-Din Babar

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Health-related quality of life in chronic kidney disease patients in low- and lower-middle income countries: a systematic review and meta-analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
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  16. Mediation effect of self-neglect in family resilience and medication adherence in older patients undergoing maintenance hemodialysis.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Muhammad Daoud ButtSchool of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang 11800, Malaysia.ORCID 0000-0001-5050-8011
Siew Chin OngSchool of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang 11800, Malaysia.ORCID 0000-0002-9750-9588
Fatima Zahid ButtLahore General Hospital, Lahore 54000, Pakistan.
Ahsan SajjadLahore General Hospital, Lahore 54000, Pakistan.ORCID 0000-0002-7759-8261
Muhammad Fawad RasoolDepartment of Pharmacy Practice, Faculty of Pharmacy, Bahauddin Zakariya University, Multan 60000, Pakistan.ORCID 0000-0002-8607-8583
Imran ImranDepartment of Pharmacology, Faculty of Pharmacy, Bahauddin Zakariya University, Multan 60000, Pakistan.ORCID 0000-0003-1337-8574
Tanveer AhmadInstitute for Advanced Biosciences (IAB), CNRS UMR5309, INSERM U1209, Grenoble Alpes University, 38400 Saint-Martin-d'Hères, France.ORCID 0000-0001-8805-0296
Faleh AlqahtaniDepartment of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0003-3924-593X
Zaheer-Ud-Din BabarDepartment of Pharmacy, University of Huddersfield, Huddersfield HD1 3DH, UK.ORCID 0000-0003-1051-3240

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundKidney failure is a global health problem with a worldwide mean prevalence rate of 13.4%. Kidney failure remains symptomless during most of the early stages until symptoms appear in the advanced stages. Kidney failure is associated with a decrease in health-related quality of life (HRQOL), deterioration in physical and mental health, and an increased risk of cardiovascular morbidity and mortality. This study aimed to evaluate the factors associated with decreased HRQOL and other factors affecting the overall health of patients. Another objective was to measure how medication adherence and depression could affect the overall HRQOL in patients with kidney failure. METHODOLOGY: The study used a prospective follow-up mix methodology approach with six-month follow-ups of patients. The participants included in the study population were those with chronic kidney disease grade 4 and kidney failure. Pre-validated and translated questionnaires (Kidney Disease Quality of Life-Short Form, Hamilton Depression Rating Scale Urdu Version, and Morisky Lewis Greens Adherence Scale) and assessment tools were used to collect data.

resultsThis study recruited 314 patients after an initial assessment based on inclusion criteria. The mean age of the study population was 54.64 ± 15.33 years. There was a 47.6% male and a 52.4% female population. Hypertension and diabetes mellitus remained the most predominant comorbid condition, affecting 64.2% and 74.6% of the population, respectively. The study suggested a significant (

conclusionsPatients on maintenance dialysis for kidney failure have a significant burden of physical and mental symptoms, depression, and low HRQOL. Given the substantial and well-known declines in physical and psychological well-being among kidney failure patients receiving hemodialysis, the findings of this research imply that these areas related to health should receive special attention in the growing and expanding population of kidney failure patients.

Indexed as

Quality of LifeRenal Insufficiency, ChronicAdultAgedDepressionFemaleHumansMaleMedication AdherenceMiddle AgedPrevalenceProspective Studiesdepressionhealth-related quality of life (HRQOL)hemodialysiskidney failuremedication adherence

Identifiers

PMID36429988
PMCPMC9690334

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.