Evidence map›Paper›PMID 36429812›Full record

ArticleInternational journal of environmental research and public health2022

The Autonomic Imbalance of Myocardial Ischemia during Exercise Stress Testing: Insight from Short-Term Heart Rate Variability Analysis.

Ping-Yen Lin, Cheng-Ting Tsai, Chang Francis Hsu, Ying-Hsiang Lee, Han-Ping Huang, Chun-Che Huang, Lawrence Yu-Min Liu, Long Hsu, Ten-Fang Yang, Po-Lin Lin

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Ping-Yen LinDepartment of Electrophyics, National Yang Ming Chiao Tung University, Hsinchu 30010, Taiwan.ORCID 0000-0002-3081-5193
Cheng-Ting TsaiCardiovascular Center, MacKay Memorial Hospital, Taipei 104217, Taiwan.
Chang Francis HsuLabfront (Kiipo Co.), Boston, MA 02067, USA.ORCID 0000-0001-9254-9364
Ying-Hsiang LeeCardiovascular Center, MacKay Memorial Hospital, Taipei 104217, Taiwan.ORCID 0000-0002-1882-9664
Han-Ping HuangLabfront (Kiipo Co.), Boston, MA 02067, USA.
Chun-Che HuangDepartment of Healthcare Administration, I-Shou University, Kaohsiung 82445, Taiwan.ORCID 0000-0001-5661-9548
Lawrence Yu-Min LiuDepartment of Medicine, MacKay Medical College, New Taipei City 25245, Taiwan.ORCID 0000-0002-2101-9574
Long HsuDepartment of Electrophyics, National Yang Ming Chiao Tung University, Hsinchu 30010, Taiwan.
Ten-Fang YangDepartment of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu 30010, Taiwan.
Po-Lin LinDivision of Cardiology, Hsinchu MacKay Memorial Hospital, Hsinchu 30071, Taiwan.
National Yang Ming Chiao Tung University · TWMackay Memorial Hospital · TWMinistry of Health and Welfare · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exercise stress testing (EST) has limited power in diagnosing obstructive coronary artery disease (CAD). The heart rate variability (HRV) analysis might increase the sensitivity of CAD detection. This study aimed to evaluate the correlation between short-term HRV and myocardial ischemia during EST, including the acceleration, maximum, and recovery stages of heart rate (HR). The HRV during EST from 19 healthy (RHC) subjects and 35 patients with CAD (25 patients with insignificant CAD (iCAD), and 10 patients with significant CAD (sCAD)) were compared. As a result, all HRV indices decreased at the maximum stage and no significant differences between iCAD and sCAD were found. The low-frequency power of heart rate signal (LF) of the RHC group recovered relatively quickly from the third to the sixth minutes after maximum HR, compared with that of the sCAD group. The relative changes of most HRV indices between maximum HR and recovery stage were lower in the sCAD group than in the RHC group, especially in LF, the standard deviation of all normal to normal intervals (SDNN), and the standard deviation in the long axis direction of the Poincaré plot analysis (SD2) indices (

Indexed as

Autonomic Nervous System DiseasesCoronary Artery DiseaseMyocardial IschemiaExercise TestFemaleHeart RateHumansPregnancycoronary artery diseaseexercise stress testingheart rate variabilitymyocardial ischemiashort-term HRV

Identifiers

PMID36429812
PMCPMC9690482
OpenAlexW4309173128

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.