ReviewInternational journal of environmental research and public health2022
Polycystic Ovarian Syndrome (PCOS): Does the Challenge End at Conception?
Review in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Investigation of trends, hot spots and effective therapies for pregnancy outcomes in polycystic ovary syndrome: a bibliometric analysis.Frontiers in medicine · 2026Pooled it
- The crosstalk between polycystic ovary syndrome and Hashimoto thyroiditis: a systematic review and meta-analysis.Frontiers in endocrinology · 2026Pooled it
- Hypothalamic Inflammation as a Critical Link Between Metabolic Dysfunction and Impaired Endometrial Receptivity in Obese Polycystic Ovary Syndrome.Physiological research · 2026Article
- Exploring the significance of fatty acid-binding protein 4 levels as a biomarker for autism spectrum disorder: a cross-sectional study.BMC psychiatry · 2026Article
- Polycystic ovarian syndrome a risk factor for non-communicable diseases: insights into recent research and prevention approaches.Journal of ovarian research · 2025Review
- The association between preconception polycystic ovary syndrome and gestational diabetes mellitus among women with and without pre-pregnancy hypertension: a cross-sectional study from Utah's Pregnancy Risk Assessment Monitoring System Survey (2016-2021).The Utah women's health review · 2025Article
- Correlation of GLUT4, LEPR , and TNF-a with endometrial receptivity in women with polycystic ovarian syndrome-induced infertility.Journal of medical biochemistry · 2025Article
- To explore the relationship between endometrial hyperemia and polycystic ovary syndrome.Open life sciences · 2025Article
- The triglyceride glucose-body mass index predicts adverse reproductive outcomes in women with polycystic ovary syndrome undergoing frozen embryo transfer.Frontiers in endocrinology · 2025Article
- Low body mass index adversely affects the live birth rate following fresh embryo transfer in Chinese women with polycystic ovary syndrome: a pilot study.Frontiers in endocrinology · 2025Article
- Curcumin mitigates polycystic ovary syndrome in mice by suppressing TLR4/MyD88/NF-κB signaling pathway activation and reducing intestinal mucosal permeability.Scientific reports · 2024Article
- Pregnancy outcomes in type 2 versus type 1 diabetes: systematic review with meta-analyses.Endocrine connections · 2024Article
- Review
- Prevalence and Diagnosis of PCOS Using Electronic Health Records: A Scoping Review and a Database Analysis.International journal of environmental research and public health · 2024Article
- Serum Expression of miR-23a-3p and miR-424-5p Indicate Specific Polycystic Ovary Syndrome Phenotypes: A Pilot Study.International journal of molecular sciences · 2024Article
- Implantation and Decidualization in PCOS: Unraveling the Complexities of Pregnancy.International journal of molecular sciences · 2024Review
- Higher Cumulative Live Birth Rate but Also Higher Late Miscarriage Risk in Non-Obese Women with Polycystic Ovary Syndrome Undergoing the First IVF/ICSI Cycle.International journal of women's health · 2024Article
- Causal relationship between fertility nutrients supplementation and PCOS risk: a Mendelian randomization study.Frontiers in endocrinology · 2024Article
- The effect of β-cell dysfunction on reproductive outcomes of PCOS undergoing IVF or ICSI embryo transfer cycles: a retrospective cohort study.Frontiers in endocrinology · 2024Article
- Pathophysiological Insight into Fatty Acid-Binding Protein-4: Multifaced Roles in Reproduction, Pregnancy, and Offspring Health.International journal of molecular sciences · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polycystic ovary syndrome (PCOS) is a prevalent condition that not only has the potential to impede conception but also represents the most common endocrine dysfunction in fertile women. It is considered a heterogeneous and multifaceted disorder, with multiple reproductive and metabolic phenotypes which differently affect the early- and long-term syndrome's risks. Undoubtedly, the impact of PCOS on infertility has attracted most of the attention of healthcare providers and investigators. However, there is growing evidence that even after conception is achieved, PCOS predisposes the parturient to several adverse pregnancy outcomes including a high risk of pregnancy-induced hypertension, spontaneous abortion, gestational diabetes, preeclampsia, and preterm birth, which increase the risks of stillbirth and neonatal death. Fetal growth abnormalities may also be more common, but the relationship is less well defined. This narrative review aims to summarize current knowledge regarding these conditions as they interplay with PCOS and concludes that although there appears to be an increase in these complications during the pregnancy of women with PCOS, there is a need for further research to clarify the possible confounding impact of obesity. Implications for clinical practice and future research are outlined.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.